ArticleJournal of clinical microbiology1992
Functional and serological analysis of type II immunoglobulin G-binding proteins expressed by pathogenic group A streptococci.
Article in Journal of clinical microbiology, 1992. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
14 citing papers in PubMed, 38 citations in OpenAlex.
- Novel Sample Preparation for Mass Spectral Analysis of Complex Biological Samples.Current proteomics · 2010Article
- Restoration of Mga function to a Streptococcus pyogenes strain (M Type 50) that is virulent in mice.Infection and immunity · 2001Article
- Absence of SpeB production in virulent large capsular forms of group A streptococcal strain 64.Infection and immunity · 2000Article
- Attenuated expression of the mga virulence regulon in an M serotype 50 mouse-virulent group A streptococcal strain.Infection and immunity · 1999Article
- DNA sequencing and gene expression of the emm gene cluster in an M50 group A streptococcus strain virulent for mice.Infection and immunity · 1996Article
- Expression of both M protein and hyaluronic acid capsule by group A streptococcal strains results in a high virulence for chicken embryos.Medical microbiology and immunology · 1996Article
- Distinct profiles of immunoglobulin G-binding-protein expression by invasive serotype M1 isolates of Streptococcus pyogenes.Clinical and diagnostic laboratory immunology · 1995Article
- Analysis of immunoglobulin G-binding-protein expression by invasive isolates of Streptococcus pyogenes.Clinical and diagnostic laboratory immunology · 1995Article
- Protein H--a bacterial surface protein with affinity for both immunoglobulin and fibronectin type III domains.The EMBO journal · 1995Article
- M-like, immunoglobulin-binding protein of Streptococcus pyogenes type M15.Current microbiology · 1994Article
- Identification of two functional forms of immunoglobulin G3-binding protein expressed by group A streptococci.Infection and immunity · 1994Article
- Analysis of genes encoding two unique type IIa immunoglobulin G-binding proteins expressed by a single group A streptococcal isolate.Infection and immunity · 1994Article
- Association of type II immunoglobulin G-binding protein expression and survival of group A streptococci in human blood.Infection and immunity · 1993Article
- Association between expression of immunoglobulin G-binding proteins by group A streptococci and virulence in a mouse skin infection model.Infection and immunity · 1993Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
Bacterial immunoglobulin-binding proteins expressed on the surface of group A streptococci represent a heterogeneous family of functionally related proteins. In this report, we describe efficient methods for extracting immunoglobulin-binding proteins and classifying them functionally and antigenically. A common characteristic of immunoglobulin-binding proteins expressed by group A streptococci appears to be the absence of internal methionine residues in the binding protein. This has enabled development of a rapid, efficient, cyanogen bromide-based extraction procedure for solubilizing these molecules from intact bacteria. Studies carried out with a series of monospecific polyclonal antibodies prepared in chickens have identified two major antigenic classes of immunoglobulin-binding proteins. The methods described in this report facilitate a rapid functional and serological screening of immunoglobulin-binding proteins that should now enable detailed epidemiological studies of the importance of these molecules in group A streptococcal infections and their relationship to other surface proteins, in particular, the antiphagocytic M protein.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.