ReviewCell proliferation2003
Isolation and characterization of functional mammary gland stem cells.
Review in Cell proliferation, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
44 citing papers in PubMed, 111 citations in OpenAlex.
- Article
- Role of Cancer Side Population Stem Cells in Ovarian Cancer Angiogenesis.Medical principles and practice : international journal of the Kuwait University, Health Science Centre · 2024Review
- A technology of a different sort: microraft arrays.Lab on a chip · 2021Review
- Immortalization of Different Breast Epithelial Cell Types Results in Distinct Mitochondrial Mutagenesis.International journal of molecular sciences · 2019Article
- Induction of a tumor-metastasis-receptive microenvironment as an unwanted and underestimated side effect of treatment by chemotherapy or radiotherapy.Journal of ovarian research · 2013Article
- Hemogenic endothelial cell specification requires c-Kit, Notch signaling, and p27-mediated cell-cycle control.Developmental cell · 2013Article
- Doxorubicin and 5-fluorouracil resistant hepatic cancer cells demonstrate stem-like properties.Cytotechnology · 2013Article
- Immunotherapy of radioresistant mammary tumors with early metastasis using molecular chaperone vaccines combined with ionizing radiation.Journal of immunology (Baltimore, Md. : 1950) · 2013Article
- Mammary gland-derived nestin-positive cell populations can be isolated from human male and female donors.Stem cell research & therapy · 2013Article
- Array of Biodegradable Microraftsfor Isolation and Implantation of Living, Adherent Cells.RSC advances · 2013Article
- Three-dimensional-engineered matrix to study cancer stem cells and tumorsphere formation: effect of matrix modulus.Tissue engineering. Part A · 2013Article
- Lgr5-expressing cells are sufficient and necessary for postnatal mammary gland organogenesis.Cell reports · 2013Article
- Ultrasound-induced release of micropallets with cells.Applied physics letters · 2012Article
- Impact of release dynamics of laser-irradiated polymer micropallets on the viability of selected adherent cells.Journal of the Royal Society, Interface · 2012Article
- Article
- Stem cell antigen-1 deficiency enhances the chemopreventive effect of peroxisome proliferator-activated receptorγ activation.Cancer prevention research (Philadelphia, Pa.) · 2012Article
- Endometrial stem cells and reproduction.Obstetrics and gynecology international · 2012Article
- Adult pancreas side population cells expand after β cell injury and are a source of insulin-secreting cells.PloS one · 2012Article
- Wortmannin induces MCF-7 breast cancer cell death via the apoptotic pathway, involving chromatin condensation, generation of reactive oxygen species, and membrane blebbing.Breast cancer (Dove Medical Press) · 2012Article
- ΔNp63α promotes cellular quiescence via induction and activation of Notch3.Cell cycle (Georgetown, Tex.) · 2011Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
Abstract
Significant advances in the stem-cell biology of several tissues, including the mammary gland, have occurred over the past several years. Recent progress on stem-cell fate determination, molecular markers, signalling pathways and niche interactions in haematopoietic, neuronal and muscle tissue may provide parallel insight into the biology of mammary epithelial stem cells. Taking advantage of approaches similar to those employed to isolate and characterize haematopoietic and epidermal stem cells, we have identified a mammary epithelial cell population with several stem/progenitor cell qualities. In this article, we review some recent data on mammary epithelial stem/progenitor cells in genetically engineered mouse models. We also discuss several potential molecular markers, including stem-cell antigen-1 (Sca-1), which may be useful for both the isolation of functional mammary epithelial stem/progenitor cells and the analysis of tumour aetiology and phenotype in genetically engineered mouse models. In different transgenic mammary tumour models, Sca-1 expression levels, as well as several other putative markers of progenitors including keratin-6, possess dramatically altered expression profiles. These data suggest that the heterogeneity of mouse models of breast cancer may partially reflect the selection or expansion of different progenitors.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.