ArticleJournal of biomolecular NMR2003
Smartnotebook: a semi-automated approach to protein sequential NMR resonance assignments.
Article in Journal of biomolecular NMR, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
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Who cites it
28 citing papers in PubMed.
- Protein NMR assignment by isotope pattern recognition.Science advances · 2024Article
- The structural and functional effects of the familial hypertrophic cardiomyopathy-linked cardiac troponin C mutation, L29Q.Journal of molecular and cellular cardiology · 2015Article
- Article
- Elucidation of isoform-dependent pH sensitivity of troponin i by NMR spectroscopy.The Journal of biological chemistry · 2012Article
- Visualizing the principal component of ¹H, ¹⁵N-HSQC NMR spectral changes that reflect protein structural or functional properties: application to troponin C.Journal of biomolecular NMR · 2011Article
- Iterative Development of an Application to Support Nuclear Magnetic Resonance Data Analysis of Proteins.Proceedings of the ... International Conference on Information Technology: New Generations. International Conference on Information Technology: New Generations · 2011Article
- A novel strategy for NMR resonance assignment and protein structure determination.Journal of biomolecular NMR · 2011Article
- A structural and functional perspective into the mechanism of Ca2+-sensitizers that target the cardiac troponin complex.Journal of molecular and cellular cardiology · 2010Article
- Structural and antimicrobial properties of human pre-elafin/trappin-2 and derived peptides against Pseudomonas aeruginosa.BMC microbiology · 2010Article
- Solution structure of the regulatory domain of human cardiac troponin C in complex with the switch region of cardiac troponin I and W7: the basis of W7 as an inhibitor of cardiac muscle contraction.Journal of molecular and cellular cardiology · 2010Article
- Proline cis/trans-isomerase Pin1 regulates peroxisome proliferator-activated receptor gamma activity through the direct binding to the activation function-1 domain.The Journal of biological chemistry · 2010Article
- Solution structure of human cardiac troponin C in complex with the green tea polyphenol, (-)-epigallocatechin 3-gallate.The Journal of biological chemistry · 2009Article
- The effect of the cosolvent trifluoroethanol on a tryptophan side chain orientation in the hydrophobic core of troponin C.Protein science : a publication of the Protein Society · 2009Article
- Highly automated protein backbone resonance assignment within a few hours: the "BATCH" strategy and software package.Journal of biomolecular NMR · 2009Article
- Automated protein structure calculation from NMR data.Journal of biomolecular NMR · 2009Article
- Automated amino acid side-chain NMR assignment of proteins using (13)C- and (15)N-resolved 3D [ (1)H, (1)H]-NOESY.Journal of biomolecular NMR · 2008Article
- Graphical interpretation of Boolean operators for protein NMR assignments.Journal of biomolecular NMR · 2008Article
- Defining the binding site of levosimendan and its analogues in a regulatory cardiac troponin C-troponin I complex.Biochemistry · 2008Article
- KUJIRA, a package of integrated modules for systematic and interactive analysis of NMR data directed to high-throughput NMR structure studies.Journal of biomolecular NMR · 2007Article
- Toward protein structure in situ: comparison of two bifunctional rhodamine adducts of troponin C.Biophysical journal · 2007Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Complete and accurate NMR spectral assignment is a prerequisite for high-throughput automated structure determination of biological macromolecules. However, completely automated assignment procedures generally encounter difficulties for all but the most ideal data sets. Sources of these problems include difficulty in resolving correlations in crowded spectral regions, as well as complications arising from dynamics, such as weak or missing peaks, or atoms exhibiting more than one peak due to exchange phenomena. Smartnotebook is a semi-automated assignment software package designed to combine the best features of the automated and manual approaches. The software finds and displays potential connections between residues, while the spectroscopist makes decisions on which connection is correct, allowing rapid and robust assignment. In addition, smartnotebook helps the user fit chains of connected residues to the primary sequence of the protein by comparing the experimentally determined chemical shifts with expected shifts derived from a chemical shift database, while providing bookkeeping throughout the assignment procedure.
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14512729What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.