Trial reportLipids2003
Chylomicron and VLDL TAG structures and postprandial lipid response induced by lard and modified lard.
Trial report in Lipids, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it, 35 citations in OpenAlex.
- Palmitic Acid Versus Stearic Acid: Effects of Interesterification and Intakes on Cardiometabolic Risk Markers - A Systematic Review.Nutrients · 2020Pooled it
- Palmitic acid-rich oils with and without interesterification lower postprandial lipemia and increase atherogenic lipoproteins compared with a MUFA-rich oil: A randomized controlled trial.The American journal of clinical nutrition · 2021Trial
- Palmitic acid in the sn-2 position decreases glucose-dependent insulinotropic polypeptide secretion in healthy adults.European journal of clinical nutrition · 2014Trial
- Trial
- Influence of interesterification of a stearic acid-rich spreadable fat on acute metabolic risk factors.Lipids · 2009Trial
- Positional distribution of decanoic acid: effect on chylomicron and VLDL TAG structures and postprandial lipemia.Lipids · 2004Trial
- Food and Drug Administration Expert Panel on Infant Formula "Operation Stork Speed" June 2025: Part 1, Nutrient Considerations.Advances in nutrition (Bethesda, Md.) · 2026Review
- Postprandial lipemia: factoring in lipemic response for ranking foods for their healthiness.Lipids in health and disease · 2017Review
- What are interesterified fats and should we be worried about them in our diet?Nutrition bulletin · 2017Article
- Effects of Lipid Structure Changed by Interesterification on Melting Property and Lipemia.Lipids · 2016Review
- Effects of triacylglycerol structure and solid fat content on fasting responses of mice.European journal of nutrition · 2016Article
- Differences in partitioning of meal fatty acids into blood lipid fractions: a comparison of linoleate, oleate, and palmitate.American journal of physiology. Endocrinology and metabolism · 2009Article
- Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Alterations in chylomicron and VLDL TAG and the magnitude of postprandial lipemia were studied in healthy volunteers after two meals of equal FA composition but different TAG FA positional distribution. Molecular level information of individual lipoprotein TAG regioisomers was obtained with a tandem MS method. The incremental area under the response curve of VLDL TAG was larger (P = 0.021) after modified lard than after lard. In plasma TAG, the difference did not quite reach statistical significance (P = 0.086). In general, there were less TAG with palmitic acid in the sn-2 position and more TAG with oleic acid in the sn-2 position in chylomicrons than in fat ingested. From 1.5 to 8 h postprandially, the proportion of individual chylomicron TAG was constant or influenced by TAG M.W. VLDL TAG regioisomerism was similar regardless of the positional distribution of fat ingested. Significant alterations were seen in VLDL TAG FA, in M.W. fractions, and in individual regioisomers with respect to time. The TAG sn-14:0-18:1-18:1 + sn-18:1-18:1-14:0, sn-16:0-16:1-18:1 + sn-18:1-16:1-16:0, and sn-16:1-18:1-18:1 + sn-18:1-18:1-16:1 decreased (P < 0.05); and sn-16:0-16:0-18:2 + sn-18:2-16:0-16:0, sn-16:0-16:0-18:1 + sn-18:1-16:0-16:0, sn-16:0-18:1-16:0, and sn-16:0-18:1-18:2 + sn-18:2-18:1-16:0 increased (P < 0.05) after both meals. In conclusion, positional distribution of TAG FA was found to affect postprandial lipid metabolism in healthy normolipidemic subjects.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.