ArticleThe Journal of cell biology2003
Peroxisome division in the yeast Yarrowia lipolytica is regulated by a signal from inside the peroxisome.
Article in The Journal of cell biology, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed, 64 citations in OpenAlex.
- Convergent and divergent mechanisms of peroxisomal and mitochondrial division.The Journal of cell biology · 2023Article
- Article
- Post-translational modifications of proteins associated with yeast peroxisome membrane: An essential mode of regulatory mechanism.Genes to cells : devoted to molecular & cellular mechanisms · 2021Review
- Utilization of Clarified Butter Sediment Waste as a Feedstock for Cost-Effective Production of Biodiesel.Foods (Basel, Switzerland) · 2019Article
- Peroxisome biogenesis, membrane contact sites, and quality control.EMBO reports · 2019Review
- Role of Pex11p in Lipid Homeostasis in Yarrowia lipolytica.Eukaryotic cell · 2015Article
- Article
- PPARα activation induces N(ε)-Lys-acetylation of rat liver peroxisomal multifunctional enzyme type 1.Lipids · 2014Article
- PEX16: a multifaceted regulator of peroxisome biogenesis.Frontiers in physiology · 2013Review
- Plant peroxisomes: biogenesis and function.The Plant cell · 2012Review
- Making two organelles from one: Woronin body biogenesis by peroxisomal protein sorting.The Journal of cell biology · 2008Article
- A signal from inside the peroxisome initiates its division by promoting the remodeling of the peroxisomal membrane.The Journal of cell biology · 2007Article
- The PEROXIN11 protein family controls peroxisome proliferation in Arabidopsis.The Plant cell · 2007Article
- Peroxisome biogenesis: the peroxisomal endomembrane system and the role of the ER.The Journal of cell biology · 2006Review
- The origin and maintenance of mammalian peroxisomes involves a de novo PEX16-dependent pathway from the ER.The Journal of cell biology · 2006Article
- Regulatory genes controlling fatty acid catabolism and peroxisomal functions in the filamentous fungus Aspergillus nidulans.Eukaryotic cell · 2006Article
- Arabidopsis peroxin 16 coexists at steady state in peroxisomes and endoplasmic reticulum.Plant physiology · 2005Article
- Dynamic ergosterol- and ceramide-rich domains in the peroxisomal membrane serve as an organizing platform for peroxisome fusion.The Journal of cell biology · 2005Article
- The peroxisome deficient Arabidopsis mutant sse1 exhibits impaired fatty acid synthesis.Plant physiology · 2004Article
- Peroxisome biogenesis and the role of protein import.Journal of cellular and molecular medicineReview
Corrections and comments
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Authors and funding
9 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We describe an unusual mechanism for organelle division. In the yeast Yarrowia lipolytica, only mature peroxisomes contain the complete set of matrix proteins. These mature peroxisomes assemble from several immature peroxisomal vesicles in a multistep pathway. The stepwise import of distinct subsets of matrix proteins into different immature intermediates along the pathway causes the redistribution of a peroxisomal protein, acyl-CoA oxidase (Aox), from the matrix to the membrane. A significant redistribution of Aox occurs only in mature peroxisomes. Inside mature peroxisomes, the membrane-bound pool of Aox interacts with Pex16p, a membrane-associated protein that negatively regulates the division of early intermediates in the pathway. This interaction inhibits the negative action of Pex16p, thereby allowing mature peroxisomes to divide.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.