ArticleGenetics2003
The extent of linkage disequilibrium and haplotype sharing around a polymorphic site.
Article in Genetics, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
13 citing papers in PubMed.
- Article
- Characterization of a Sex-Determining Region and Its Genomic Context via Statistical Estimates of Haplotype Frequencies in Daughters and Sons Sequenced in Pools.Genome biology and evolution · 2021Article
- Article
- Selective Sweeps Under Dominance and Inbreeding.G3 (Bethesda, Md.) · 2020Article
- A Coalescent Model for a Sweep of a Unique Standing Variant.Genetics · 2015Article
- Microevolutionary dynamics of a macroevolutionary key innovation in a Lepidopteran herbivore.BMC evolutionary biology · 2010Article
- Recombination at Prunus S-locus region SLFL1 gene.Genetics · 2008Article
- Evidence of gene conversion in the evolutionary process of the codon 41/42 (-CTTT) mutation causing beta-thalassemia in southern China.Journal of molecular evolution · 2008Article
- Low levels of polymorphism in genes that control the activation of defense response in Arabidopsis thaliana.Genetics · 2008Article
- A genome-wide survey of R gene polymorphisms in Arabidopsis.The Plant cell · 2006Article
- Linkage disequilibrium between incompatibility locus region genes in the plant Arabidopsis lyrata.Genetics · 2006Article
- A nonparametric test reveals selection for rapid flowering in the Arabidopsis genome.PLoS biology · 2006Article
- Article
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Various expressions related to the length of a conserved haplotype around a polymorphism of known frequency are derived. We obtain exact expressions for the probability that no recombination has occurred in a sample or subsample. We obtain an approximation for the probability that no recombination that could give rise to a detectable recombination event (through the four-gamete test) has occurred. The probabilities can be used to obtain approximate distributions for the length of variously defined haplotypes around a polymorphic site. The implications of our results for data analysis, and in particular for detecting selection, are discussed.
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Registered trials
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