Evidence map›Paper›PMID 14503436›Full record

Trial reportNeurorehabilitation and neural repair2003

Methods for a randomized trial of weight-supported treadmill training versus conventional training for walking during inpatient rehabilitation after incomplete traumatic spinal cord injury.

Bruce H Dobkin, David Apple, Hugues Barbeau, Michele Basso, Andrea Behrman, Dan Deforge, John Ditunno, Gary Dudley, Robert Elashoff, Lisa Fugate and 3 more

Registry-linked trialAbstract readClinical TrialRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Neurorehabilitation and neural repair, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00006429 (Locomotor Therapy Trial for Spinal Cord Injury), which is not on this map. Cited by 47 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
47citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT00006429 phase2completednot on this map

Locomotor Therapy Trial for Spinal Cord Injury

TypeinterventionalSponsorEunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)Ran1999 to 2004Enrolled200ConditionsSpinal Cord InjuryArmsbody weight-supported treadmill training
3 · Its place in the literature

Who cites it

47 citing papers in PubMed, 3 syntheses or guidelines pooled it.

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  3. Locomotor training for walking after spinal cord injury.The Cochrane database of systematic reviews · 2012
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Bruce H DobkinDepartment of Neurology, Neurologic Rehabilitation and Research Program, University of California Los Angeles, Reed Neurologic, USA. bdobkin@mednet.ucla.edu
David Apple
Hugues Barbeau
Michele Basso
Andrea Behrman
Dan Deforge
John Ditunno
Gary Dudley
Robert Elashoff
Lisa Fugate
Susan Harkema
Michael Saulino
Michael Scott

Funding

LOCOMOTOR THERAPY TRIAL FOR SPINAL CORD INJURYU01HD037439 · NICHD · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI DOBKIN, BRUCE HARVEY · 1999 to 2003
$3.3M
NICHD NIH HHS HD 37349NICHD NIH HHS U01 HD037439
6 · The paper itself

Abstract

The authors describe the rationale and methodology for the first prospective, multicenter, randomized clinical trial (RCT) of a task-oriented walking intervention for subjects during early rehabilitation for an acute traumatic spinal cord injury (SCI). The experimental strategy, body weight-supported treadmill training (BWSTT), allows physical therapists to systematically train patients to walk on a treadmill at increasing speeds typical of community ambulation with increasing weight hearing. The therapists provide verbal and tactile cues to facilitate the kinematic, kinetic, and temporal features of walking. Subjects were randomly assigned to a conventional therapy program for mobility versus the same intensity and duration of a combination of BWSTT and over-ground locomotor retraining. Subjects had an incomplete SCI (American Spinal Injury Association grades B, C, and D) from C-4 to T-10 (upper motoneuron group) or from T-11 to L-3 (lower motoneuron group). Within 8 weeks of a SCI, 146 subjects were entered for 12 weeks of intervention. The 2 single-blinded primary outcome measures are the level of independence for ambulation and, for those who are able to walk, the maximal speed for walking 50 feet, tested 6 and 12 months after randomization. The trial's methodology offers a model for the feasibility of translating neuroscientific experiments into a RCT to develop evidence-based rehabilitation practices.

Indexed as

Physical Therapy ModalitiesExercise TestHumansInpatientsMulticenter Studies as TopicOutcome Assessment, Health CarePatient SelectionProspective StudiesRandomized Controlled Trials as TopicSample SizeSpinal Cord InjuriesWalking

Identifiers

PMID14503436
PMCPMC4162674

What OpenQuestion holds

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Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.