ArticleMolecular and cellular biology1992
Identification of a cysteine-rich receptor for fibroblast growth factors.
Article in Molecular and cellular biology, 1992. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed, 122 citations in OpenAlex.
- Inhibition of TOR inCells · 2019Article
- Morphometric alterations of Golgi apparatus in Alzheimer's disease are related to tau hyperphosphorylation.Neurobiology of disease · 2017Article
- Changes in the Golgi Apparatus of Neocortical and Hippocampal Neurons in the Hibernating Hamster.Frontiers in neuroanatomy · 2015Article
- E-selectin ligand 1 regulates bone remodeling by limiting bioactive TGF-β in the bone microenvironment.Proceedings of the National Academy of Sciences of the United States of America · 2013Article
- Haploinsufficiency of E-selectin ligand-1 is associated with reduced atherosclerotic plaque macrophage content while complete deficiency leads to early embryonic lethality in mice.Atherosclerosis · 2012Article
- NUDT6, the FGF-2's antisense gene, showed associations with fat deposition related traits in pigs.Molecular biology reports · 2012Article
- Identification of host factors involved in coronavirus replication by quantitative proteomics analysis.Proteomics · 2011Article
- E-selectin ligand-1 regulates growth plate homeostasis in mice by inhibiting the intracellular processing and secretion of mature TGF-beta.The Journal of clinical investigation · 2010Article
- Glycosylation in immune cell trafficking.Immunological reviews · 2009Review
- Complete identification of E-selectin ligands on neutrophils reveals distinct functions of PSGL-1, ESL-1, and CD44.Immunity · 2007Article
- Direct and heterologous approaches to identify the LET-756/FGF interactome.BMC genomics · 2006Article
- NoBP, a nuclear fibroblast growth factor 3 binding protein, is cell cycle regulated and promotes cell growth.Molecular and cellular biology · 2001Article
- Uptake and intracellular transport of acidic fibroblast growth factor: evidence for free and cytoskeleton-anchored fibroblast growth factor receptors.Molecular biology of the cell · 1999Article
- Identification and characterization of an intracellular protein complex that binds fibroblast growth factor-2 in bovine brain.The Biochemical journal · 1999Article
- Cloning of an intracellular protein that binds selectively to mitogenic acidic fibroblast growth factor.The Biochemical journal · 1998Article
- Latent transforming growth factor-beta complex in Chinese hamster ovary cells contains the multifunctional cysteine-rich fibroblast growth factor receptor, also termed E-selectin-ligand or MG-160.The Biochemical journal · 1997Article
- Differentially expressed fibroblast growth factors regulate skeletal muscle development through autocrine and paracrine mechanisms.The Journal of cell biology · 1996Article
- In Alzheimer's disease the Golgi apparatus of a population of neurons without neurofibrillary tangles is fragmented and atrophic.The American journal of pathology · 1996Article
- Fibroblast growth factor overexpressing breast carcinoma cells as models of angiogenesis and metastasis.Breast cancer research and treatment · 1996Article
- A requirement for fibroblast growth factor in regulation of skeletal muscle growth and differentiation cannot be replaced by activation of platelet-derived growth factor signaling pathways.Molecular and cellular biology · 1995Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
The fibroblast growth factor (FGF) family consists of seven members whose activities are thought to be mediated by multiple receptors. Here we describe the cDNA cloning, expression, and characterization of a cysteine-rich FGF receptor (CFR) that is distinct from previously identified FGF receptors. The deduced amino acid sequence for CFR suggests that it is an integral membrane protein containing a large extracellular domain comprising 16 cysteine-rich repeated units and an intracellular domain of 13 amino acids. No reported sequences exhibit significant homologies to either the repeated extracellular motif or to the entire CFR amino acid sequence. Several CFR transcripts are present in embryonic chick tissue, suggesting that CFR undergoes alternate mRNA splicing or that related genes are present. Chinese hamster ovary cells transfected with the CFR cDNA express a 150-kDa polypeptide that binds FGF-1, FGF-2, and FGF-4 but does not bind several non-FGF family members. The high degree of evolutionary conservation among vertebrate CFRs and its ability to bind three different FGFs with high affinity suggest that this unique receptor plays an important role in FGF biology.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.