ArticleThe Biochemical journal1992
A positive regulator of the ribosomal protein gene, beta factor, belongs to the ETS oncoprotein family.
Article in The Biochemical journal, 1992. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
10 citing papers in PubMed, 26 citations in OpenAlex.
- Placing the RPL32 Promoter Upstream of a Second Promoter Results in a Strongly Increased Number of Stably Transfected Mammalian Cell Lines That Display High Protein Expression Levels.Biotechnology research international · 2011Article
- hDREF regulates cell proliferation and expression of ribosomal protein genes.Molecular and cellular biology · 2007Article
- The architecture of mammalian ribosomal protein promoters.BMC evolutionary biology · 2005Article
- Functional domains of transcription factor hGABP beta1/E4TF1-53 required for nuclear localization and transcription activation.Nucleic acids research · 1996Article
- A novel transcriptional initiator activity of the GABP factor binding ets sequence repeat from the murine cytochrome c oxidase Vb gene.Gene expression · 1995Article
- Regional mapping of two subunits of transcription factor E4TF1 to human chromosome.Japanese journal of cancer research : Gann · 1995Article
- Structure and function of ribosomal protein S4 genes on the human and mouse sex chromosomes.Molecular and cellular biology · 1994Article
- Transcriptional activation through the tetrameric complex formation of E4TF1 subunits.The EMBO journal · 1994Article
- XrpFI, an amphibian transcription factor composed of multiple polypeptides immunologically related to the GA-binding protein alpha and beta subunits, is differentially expressed during Xenopus laevis development.Molecular and cellular biology · 1993Article
- Comparative utilization of transcription factor GABP by the promoters of ribosomal protein genes rpL30 and rpL32.Gene expression · 1993Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The beta factor, which interacts with the rpL32 promoter, binds to the sequence 5'-GAGCCGGAAGTG and trans-activates this gene. Comparison of the DNA sequences bound by the beta factor with those bound by other known DNA-binding proteins revealed that the ETS proteins interact with similar DNA sequences. Consequently we have examined the relationship of the beta factor to the several ETS proteins so far reported. Antibody and oligonucleotide competition experiments, performed by using electrophoretic shift analysis, revealed that the beta factor contains ETS epitopes and that it is immunologically related to both of the GA-binding proteins (GABPs), implying that the beta factor may consist of two separate protein subunits.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.