ArticleBiophysical journal1992
Protein dynamics and 1/f noise.
Article in Biophysical journal, 1992. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed.
- Possible role of interference, protein noise, and sink effects in nonphotochemical quenching in photosynthetic complexes.Journal of mathematical biology · 2017Article
- Frequency response of a protein to local conformational perturbations.PLoS computational biology · 2013Article
- Fractal symmetry of protein interior: what have we learned?Cellular and molecular life sciences : CMLS · 2011Review
- Ion channel gating: a first-passage time analysis of the Kramers type.Proceedings of the National Academy of Sciences of the United States of America · 2002Article
- Characterization of inositol-1,4,5-trisphosphate-gated channels in the plasma membrane of rat olfactory neurons.Biophysical journal · 1999Article
- Antigen-antibody binding kinetics for biosensors. Changes in the fractal dimension (surface roughness) and in the binding rate coefficient.Applied biochemistry and biotechnology · 1996Review
- Nonlinear kinetics of ferritin adsorption.Biophysical journal · 1993Article
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Authors and funding
2 authors.
Funding
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Abstract
It has long been recognized that protein dynamical processes occur over a wide temporal range. However, the functionality of this spectrum of events remains unclear. In this work, a generalized noise function analysis is applied to a collection of diverse protein dynamical systems. It is shown that a power law model with an oscillatory component can adequately describe the time course of a variety of processes. These results suggest that under the appropriate conditions, proteins are in a metastable state. A microscopic, chemical kinetic model based on a Poisson distribution of activation energies is presented. From this model specific functional forms for the parameters of the generalized noise model can be derived. Additionally, a model is presented to described kinetic hole burning effects observed at low temperatures. Scaling laws are derived for these models that provide a connection with the generalized noise analysis.
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Registered trials
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