ArticleThe Biochemical journal1992
Different triggers for calcium oscillations in mouse eggs involve a ryanodine-sensitive calcium store.
Article in The Biochemical journal, 1992. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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Who cites it
23 citing papers in PubMed, 165 citations in OpenAlex.
- Sperm induce a secondary increase in ATP levels in mouse eggs that is independent of Ca2+ oscillations.The Biochemical journal · 2023Article
- Inositol-1,4,5-Trisphosphate Receptor-1 and -3 and Ryanodine Receptor-3 May Increase Ooplasmic CaThe journal of poultry science · 2022Article
- Increasing associations between defects in phospholipase C zeta and conditions of male infertility: not just ICSI failure?Journal of assisted reproduction and genetics · 2020Review
- Mutational analysis of IZUMO1R in women with fertilization failure and polyspermy after in vitro fertilization.Journal of assisted reproduction and genetics · 2018Article
- Ion Channel Function During Oocyte Maturation and Fertilization.Frontiers in cell and developmental biology · 2018Review
- Signal transduction in mammalian oocytes during fertilization.Cell and tissue research · 2016Review
- Role of caspase-3 cleaved IP3 R1 on Ca(2+) homeostasis and developmental competence of mouse oocytes and eggs.Journal of cellular physiology · 2014Article
- RyR channel-mediated increase of cytosolic free calcium level signals cyclin B1 degradation during abortive spontaneous egg activation in rat.In vitro cellular & developmental biology. Animal · 2014Article
- TRPV3 channels mediate strontium-induced mouse-egg activation.Cell reports · 2013Article
- Regulation of inositol 1,4,5-trisphosphate receptor function during mouse oocyte maturation.Journal of cellular physiology · 2012Article
- Calcium signalling in early embryos.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2008Review
- Mouse oocytes fertilised by ICSI during in vitro maturation retain the ability to be activated after refertilisation in metaphase II and can generate Ca2+ oscillations.BMC developmental biology · 2007Article
- Calcium at fertilization and in early development.Physiological reviews · 2006Review
- Voltage-sensitive equilibrium between two states within a ryanoid-modified conductance state of the ryanodine receptor channel.Biophysical journal · 2005Article
- Role of the nitric oxide/cyclic GMP/Ca2+ signaling pathway in the pyrogenic effect of interleukin-1beta.Molecular neurobiology · 2002Review
- The interaction of a neutral ryanoid with the ryanodine receptor channel provides insights into the mechanisms by which ryanoid binding is modulated by voltage.The Journal of general physiology · 2000Article
- Different Ca2+-releasing abilities of sperm extracts compared with tissue extracts and phospholipase C isoforms in sea urchin egg homogenate and mouse eggs.The Biochemical journal · 2000Article
- The soluble sperm factor that causes Ca2+ release from sea-urchin (Lytechinus pictus) egg homogenates also triggers Ca2+ oscillations after injection into mouse eggs.The Biochemical journal · 1999Article
- Interleukin-1 beta stimulation of 45Ca2+ release from rat striatal slices.British journal of pharmacology · 1996Article
- Phospholipase C in mouse oocytes: characterization of beta and gamma isoforms and their possible involvement in sperm-induced Ca2+ spiking.The Biochemical journal · 1996Article
Corrections and comments
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Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Relative intracellular free Ca2+ concentrations ([Ca2+]i) were monitored in mature unfertilized mouse eggs by measuring fluorescence of intracellular fluo3. A number of different agents were found to cause sustained repetitive transient [Ca2+]i oscillations. These were microinjection of a cytosolic sperm factor, sustained injection of Ins-(1,4,5)P1, or extracellular addition of the thiol reagent thimerosal. Stimulating G-protein activity by injection of guanosine 5'-[gamma-thio]triphosphate plus application of carbachol also caused [Ca2+]i oscillations, but less reliably than other stimuli. A role for Ca(2+)-induced Ca2+ release and a ryanodine-sensitive Ca2+ channel in mouse eggs was suggested by the finding that microinjection, or external addition, of ryanodine also caused [Ca2+]i increases. Furthermore, ryanodine, along with thimerosal, increased the sensitivity of eggs to Ca(2+)-induced [Ca2+]i oscillations. When ryanodine was added to eggs oscillating in response to the sperm factor, InsP3 or thimerosal, it caused a decrease in amplitude of oscillations and eventually a block of [Ca2+]i oscillations associated with a sustained elevation of [Ca2+]i. These data suggest that a ryanodine-sensitive Ca(2+)-release mechanism exists in mouse eggs and that a ryanodine-sensitive Ca2+ store plays a role in generating intracellular [Ca2+]i oscillations.
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