ArticleAmerican journal of human genetics1992
Structure and chromosomal localization of the human antidiuretic hormone receptor gene.
Article in American journal of human genetics, 1992. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
23 citing papers in PubMed, 130 citations in OpenAlex.
- Exploring the diversity of AVPR2 in Primates and its evolutionary implications.Genetics and molecular biology · 2023Article
- Clinical, Genetic and Functional Characterization of a NovelJournal of personalized medicine · 2022Article
- Rapid development of vasopressin resistance in dietary KAmerican journal of physiology. Renal physiology · 2021Article
- Article
- Focus on neonatal and infantile onset of nephrogenic syndrome of inappropriate antidiuresis: 12 years later.Pediatric nephrology (Berlin, Germany) · 2019Review
- Hereditary Nephrogenic Diabetes Insipidus: Pathophysiology and Possible Treatment. An Update.International journal of molecular sciences · 2017Review
- Mutations of Vasopressin Receptor 2 Including Novel L312S Have Differential Effects on Trafficking.Molecular endocrinology (Baltimore, Md.) · 2016Article
- Novel mutations associated with nephrogenic diabetes insipidus. A clinical-genetic study.European journal of pediatrics · 2015Article
- Oxytocin and Vasopressin Receptor Gene Polymorphisms: Role in Social and Psychiatric Traits.Frontiers in neuroscience · 2015Review
- X-Linked Recessive form of Nephrogenic Diabetes Insipidus in a 7-Year-Old Boy.Balkan journal of medical genetics : BJMG · 2014Article
- A large deletion of the AVPR2 gene causing severe nephrogenic diabetes insipidus in a Turkish family.Endocrine · 2014Article
- Aquaporin-2: new mutations responsible for autosomal-recessive nephrogenic diabetes insipidus-update and epidemiology.Clinical kidney journal · 2012Article
- Analysis of a novel AVPR2 mutation in a family with nephrogenic diabetes insipidus.International journal of clinical and experimental medicine · 2011Article
- Nephrogenic diabetes insipidus (NDI): clinical, laboratory and genetic characterization of five Brazilian patients.Clinics (Sao Paulo, Brazil) · 2009Article
- Article
- Congenital nephrogenic diabetes insipidus presented with bilateral hydronephrosis: genetic analysis of V2R gene mutations.Yonsei medical journal · 2006Article
- A novel deletion mutation in the arginine vasopressin receptor 2 gene and skewed X chromosome inactivation in a female patient with congenital nephrogenic diabetes insipidus.Journal of endocrinological investigation · 2004Article
- Generation and phenotype of mice harboring a nonsense mutation in the V2 vasopressin receptor gene.The Journal of clinical investigation · 2000Article
- Binding-, intracellular transport-, and biosynthesis-defective mutants of vasopressin type 2 receptor in patients with X-linked nephrogenic diabetes insipidus.The Journal of clinical investigation · 1995Article
- Structure, characterization, and expression of the rat oxytocin receptor gene.Proceedings of the National Academy of Sciences of the United States of America · 1995Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
Applying a genomic DNA-expression approach, we cloned the gene and cDNA coding for the human anti-diuretic hormone receptor, also called "vasopressin V2 receptor" (V2R). The nucleotide sequence of both cloned DNAs provided the information to elucidate the structure of the isolated transcriptional unit. The structure of this gene is unusual in that it is the first G protein-coupled receptor gene that contains two very small intervening sequences, the second of which separates the region encoding the seventh transmembrane region from the rest of the open reading frame. The sequence information was used to synthesize appropriate oligonucleotides to be used as primers in the PCR. The V2R gene was localized by PCR using DNA from hybrid cells as template. The gene was found to reside in the q28-qter portion of the human X chromosome, a region identified as the locus for congenital nephrogenic diabetes insipidus.
Indexed as
Identifiers
1415251PMC1682836W1924144106What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.