ArticleProceedings of the National Academy of Sciences of the United States of America1992
Mapping genes in the mouse using single-strand conformation polymorphism analysis of recombinant inbred strains and interspecific crosses.
Article in Proceedings of the National Academy of Sciences of the United States of America, 1992. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 72 citations in OpenAlex.
- GSK-3 signaling in developing cortical neurons is essential for radial migration and dendritic orientation.eLife · 2014Article
- The gene encoding the multispecific organic anion transporter (Cmoat) of the hepatocyte canalicular membrane maps to mouse chromosome 19.Mammalian genome : official journal of the International Mammalian Genome Society · 1998Article
- Expansion of the pig comparative map by expressed sequence tags (EST) mapping.Mammalian genome : official journal of the International Mammalian Genome Society · 1997Article
- Genetic mapping of 262 loci derived from expressed sequences in a murine interspecific cross using single-strand conformational polymorphism analysis.Genome research · 1997Article
- Mapping of 22 expressed sequence tags isolated from a porcine small intestine cDNA library.Mammalian genome : official journal of the International Mammalian Genome Society · 1997Article
- Murine monocyte chemoattractant protein (MCP)-5: a novel CC chemokine that is a structural and functional homologue of human MCP-1.The Journal of experimental medicine · 1997Article
- Linkage mapping of Emx2 to mouse chromosome 19.Mammalian genome : official journal of the International Mammalian Genome Society · 1997Article
- Human homologue sequences to the Drosophila dishevelled segment-polarity gene are deleted in the DiGeorge syndrome.American journal of human genetics · 1996Article
- Mapping of the MEK kinase gene (Mekk) to mouse chromosome 13 and human chromosome 5.Mammalian genome : official journal of the International Mammalian Genome Society · 1995Article
- A high-resolution map of the brown (b, Tyrp1) deletion complex of mouse chromosome 4.Mammalian genome : official journal of the International Mammalian Genome Society · 1995Article
- Haplotype analysis of intra-specific backcross curly-tail mice confirms the localization of ct to chromosome 4.Mammalian genome : official journal of the International Mammalian Genome Society · 1995Article
- Genetic map of the region surrounding the retrovirus restriction locus, Fv1, on mouse chromosome 4.Mammalian genome : official journal of the International Mammalian Genome Society · 1995Article
- A genetic linkage map of the mouse using restriction landmark genomic scanning (RLGS).Genetics · 1994Article
- Mapping of PCR-based markers for mouse chromosome 4 on a backcross penetrant for the misty (m) mutation.Mammalian genome : official journal of the International Mammalian Genome Society · 1994Article
- Article
- Arbitrarily primed PCR fingerprints resolved on SSCP gels.Nucleic acids research · 1994Article
- CD19 maps to a region of conservation between human chromosome 16 and mouse chromosome 7.Immunogenetics · 1994Article
- TAP1 alleles in insulin-dependent diabetes mellitus: a newly defined centromeric boundary of disease susceptibility.Proceedings of the National Academy of Sciences of the United States of America · 1993Article
- Mapping the midkine family of developmentally regulated signaling molecules.Mammalian genome : official journal of the International Mammalian Genome Society · 1993Article
- Single-strand conformation polymorphism (SSCP) analysis as a tool for genetic mapping.Mammalian genome : official journal of the International Mammalian Genome Society · 1993Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
We have utilized a PCR-based analysis of single-strand conformation polymorphisms to identify polymorphisms that can be used for mapping cloned DNA sequences in the mouse. We have found that single-strand conformation polymorphism analysis of sequences that are potentially less subject to conservation (i.e., intron and 3' untranslated regions) is a relatively efficient means of detecting polymorphisms between inbred strains. Fifty percent of the tested primer pairs were polymorphic between inbred strains and 90% were polymorphic between mouse species, which is a frequency comparable to that found for microsatellite repeat sequences. We have found that this technique can be readily used to determine the strain distribution pattern in a recombinant inbred series and is a simple and rapid means to obtain a map position for cloned sequences. When this strategy was tested on a number of previously mapped cloned genes, the strain distribution patterns obtained were consistent with that to be expected on the basis of the known map position. We also tested the utility of this approach for characterizing genes that have not been previously mapped. Dvl, the mouse homolog of the putative Drosophila dishevelled gene, and Adfp, encoding an adipocyte differentiation-related protein, were found to map to chromosome 4. These results were confirmed using single-strand conformation polymorphism analysis of an interspecific backcross.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.