ArticleNucleic acids research1992
Sequence comparison of new prokaryotic and mitochondrial members of the polypeptide chain release factor family predicts a five-domain model for release factor structure.
Article in Nucleic acids research, 1992. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
21 citing papers in PubMed, 42 citations in OpenAlex.
- Article
- Interactions between peptidyl tRNA hydrolase homologs and the ribosomal release factor Mrf1 in S. pombe mitochondria.Mitochondrion · 2013Article
- YaeJ is a novel ribosome-associated protein in Escherichia coli that can hydrolyze peptidyl-tRNA on stalled ribosomes.Nucleic acids research · 2011Article
- The codon specificity of eubacterial release factors is determined by the sequence and size of the recognition loop.RNA (New York, N.Y.) · 2010Article
- Bioinformatic, structural, and functional analyses support release factor-like MTRF1 as a protein able to decode nonstandard stop codons beginning with adenine in vertebrate mitochondria.RNA (New York, N.Y.) · 2010Article
- Diverse bacterial genomes encode an operon of two genes, one of which is an unusual class-I release factor that potentially recognizes atypical mRNA signals other than normal stop codons.Biology direct · 2006Article
- Construction of an in vivo nonsense readthrough assay system and functional analysis of ribosomal proteins S12, S4, and S5 in Bacillus subtilis.Journal of bacteriology · 2001Article
- The ribosomal binding and peptidyl-tRNA hydrolysis functions of Escherichia coli release factor 2 are linked through residue 246.RNA (New York, N.Y.) · 2000Article
- Temporal expression of the Bacillus subtilis secA gene, encoding a central component of the preprotein translocase.Journal of bacteriology · 1999Article
- Suppression of TGA mutations in the Bacillus subtilis spoIIR gene by prfB mutations.Journal of bacteriology · 1998Article
- Does disparate occurrence of autoregulatory programmed frameshifting in decoding the release factor 2 gene reflect an ancient origin with loss in independent lineages?Journal of bacteriology · 1998Article
- Conserved motifs in prokaryotic and eukaryotic polypeptide release factors: tRNA-protein mimicry hypothesis.Proceedings of the National Academy of Sciences of the United States of America · 1996Article
- Identification of cutC and cutF (nlpE) genes involved in copper tolerance in Escherichia coli.Journal of bacteriology · 1995Article
- The Bacillus subtilis sigma D-dependent operon encoding the flagellar proteins FliD, FliS, and FliT.Journal of bacteriology · 1994Article
- Protein synthesis in mitochondria.Molecular biology reports · 1994Review
- Termination of protein synthesis.Molecular biology reports · 1994Review
- PET112, a Saccharomyces cerevisiae nuclear gene required to maintain rho+ mitochondrial DNA.Current genetics · 1994Article
- Single point mutations in domain II of the yeast mitochondrial release factor mRF-1 affect ribosome binding.Nucleic acids research · 1993Article
- Termination of translation in bacteria may be modulated via specific interaction between peptide chain release factor 2 and the last peptidyl-tRNA(Ser/Phe).Nucleic acids research · 1993Article
- The yeast nuclear gene MRF1 encodes a mitochondrial peptide chain release factor and cures several mitochondrial RNA splicing defects.Nucleic acids research · 1992Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We have recently reported the cloning and sequencing of the gene for the mitochondrial release factor mRF-1. mRF-1 displays high sequence similarity to the bacterial release factors RF-1 and RF-2. A database search for proteins resembling these three factors revealed high similarities to two amino acid sequences deduced from unassigned genomic reading frames in Escherichia coli and Bacillus subtilis. The amino acid sequence derived from the Bacillus reading frame is 47% identical to E.coli and Salmonella typhimurium RF-2, strongly suggesting that it represents B.subtilis RF-2. Our comparison suggests that the expression of the B.subtilis gene is, like that of the E.coli and S. typhimurium RF-2 genes, autoregulated by a stop codon dependent +1 frameshift. A comparison of prokaryotic and mitochondrial release factor sequences, including the putative B.subtilis RF-2, leads us to propose a five-domain model for release factor structure. Possible functions of the various domains are discussed.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.