ReviewMicrobiological reviews1992
Mechanism of action of regulatory proteins encoded by complex retroviruses.
Review in Microbiological reviews, 1992. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 122 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
122 citing papers in PubMed, 297 citations in OpenAlex.
- Foamy Viruses, Bet, and APOBEC3 Restriction.Viruses · 2021Review
- Studies of endogenous retroviruses reveal a continuing evolutionary saga.Nature reviews. Microbiology · 2012Review
- Xenotropic murine leukemia virus-related virus establishes an efficient spreading infection and exhibits enhanced transcriptional activity in prostate carcinoma cells.Journal of virology · 2010Article
- Article
- Tat-SF1 is not required for Tat transactivation but does regulate the relative levels of unspliced and spliced HIV-1 RNAs.PloS one · 2009Article
- Article
- Article
- Using an emissive uridine analogue for assembling fluorescent HIV-1 TAR constructs.Tetrahedron · 2007Article
- Fluorescent HIV-1 Dimerization Initiation Site: design, properties, and use for ligand discovery.Journal of the American Chemical Society · 2007Article
- Characterization of functional domains of equine infectious anemia virus Rev suggests a bipartite RNA-binding domain.Journal of virology · 2006Article
- Identifying interaction sites in "recalcitrant" proteins: predicted protein and RNA binding sites in rev proteins of HIV-1 and EIAV agree with experimental data.Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing · 2006Article
- Human T-cell leukemia virus type 1 expressing nonoverlapping tax and rex genes replicates and immortalizes primary human T lymphocytes but fails to replicate and persist in vivo.Journal of virology · 2005Article
- Foamy virus Bet proteins function as novel inhibitors of the APOBEC3 family of innate antiretroviral defense factors.Journal of virology · 2005Article
- Critical role of hnRNP A1 in HTLV-1 replication in human transformed T lymphocytes.Retrovirology · 2005Article
- Sam68 is absolutely required for Rev function and HIV-1 production.Nucleic acids research · 2005Article
- Human immunodeficiency virus type 2 Gag interacts specifically with PRP4, a serine-threonine kinase, and inhibits phosphorylation of splicing factor SF2.Journal of virology · 2004Article
- Viral regulation of mRNA export.Journal of virology · 2004Article
- Potential of zoonotic transmission of non-primate foamy viruses to humans.Journal of veterinary medicine. B, Infectious diseases and veterinary public health · 2003Review
- Stable expression of primary human immunodeficiency virus type 1 structural gene products by use of a noncytopathic sindbis virus vector.Journal of virology · 2002Article
- Modulation of human immunodeficiency virus 1 replication by interferon regulatory factors.The Journal of experimental medicine · 2002Article
62 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
Abstract
Complex retroviruses are distinguished by their ability to control the expression of their gene products through the action of virally encoded regulatory proteins. These viral gene products modulate both the quantity and the quality of viral gene expression through regulation at both the transcriptional and posttranscriptional levels. The most intensely studied retroviral regulatory proteins, termed Tat and Rev, are encoded by the prototypic complex retrovirus human immunodeficiency virus type 1. However, considerable information also exists on regulatory proteins encoded by human T-cell leukemia virus type I, as well as several other human and animal complex retroviruses. In general, these data demonstrate that retrovirally encoded transcriptional trans-activators can exert a similar effect by several very different mechanisms. In contrast, posttranscriptional regulation of retroviral gene expression appears to occur via a single pathway that is probably dependent on the recruitment of a highly conserved cellular cofactor. These two shared regulatory pathways are proposed to be critical to the ability of complex retroviruses to establish chronic infections in the face of an ongoing host immune response.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.