Type 1 (insulin-dependent) diabetes mellitus and nitric oxide.

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

22 citing papers in PubMed.

1. Diabetes Associated Metabolomic Perturbations in NOD Mice.Metabolomics : Official journal of the Metabolomic Society · 2015
   Article
2. Biomedical implications of heavy metals induced imbalances in redox systems.BioMed research international · 2014
   Review
3. Early renal histological changes in alloxan-induced diabetic rats.International journal of molecular and cellular medicine · 2014
   Article
4. Suppressive effects of a selective inducible nitric oxide synthase (iNOS) inhibitor on pancreatic beta-cell dysfunction.Diabetologia · 2003
   Article
5. Genetic control of non obese diabetic mice susceptibility to high-dose streptozotocin-induced diabetes.Diabetologia · 2003
   Article
6. Aspects of novel sites of regulation of the insulin stimulus-secretion coupling in normal and diabetic pancreatic islets.Endocrine · 1998
   Review
7. The harmony of the spheres: inducible nitric oxide synthase and related genes in pancreatic beta cells.Diabetologia · 1996
   Review
8. The involvement of endogenous nitric oxide in vagal-cholinergic stimulation of exocrine and endocrine pancreas in dogs.International journal of pancreatology : official journal of the International Association of Pancreatology · 1995
   Article
9. Heat shock induces resistance in rat pancreatic islet cells against nitric oxide, oxygen radicals and streptozotocin toxicity in vitro.The Journal of clinical investigation · 1995
   Article
10. The emerging multifaceted roles of nitric oxide.Annals of surgery · 1995
    Review
11. Intraislet release of interleukin 1 inhibits beta cell function by inducing beta cell expression of inducible nitric oxide synthase.The Journal of experimental medicine · 1995
    Article
12. Neuronal and endothelial nitric oxide synthase immunoreactivity and NADPH-diaphorase staining in rat and human pancreas: influence of fixation.Histochemistry · 1994
    Article
13. Transgenic copper/zinc superoxide dismutase modulates susceptibility to type I diabetes.Proceedings of the National Academy of Sciences of the United States of America · 1994
    Article
14. Major species differences between humans and rodents in the susceptibility to pancreatic beta-cell injury.Proceedings of the National Academy of Sciences of the United States of America · 1994
    Article
15. On the pathogenesis of IDDM.Diabetologia · 1994
    Review
16. Primary cultures of rat islet capillary endothelial cells. Constitutive and cytokine-inducible macrophagelike nitric oxide synthases are expressed and activities regulated by glucose concentration.The American journal of pathology · 1994
    Article
17. Reversibility of interleukin-1 beta-induced islet destruction and dysfunction by the inhibition of nitric oxide synthase.The Biochemical journal · 1994
    Article
18. Serum biopterin--a novel marker for immune activation during pre-diabetes in the BB rat.Diabetologia · 1994
    Article
19. Cytokines suppress human islet function irrespective of their effects on nitric oxide generation.The Journal of clinical investigation · 1994
    Article
20. The role of nitric oxide in the pathogenesis of spontaneous murine autoimmune disease: increased nitric oxide production and nitric oxide synthase expression in MRL-lpr/lpr mice, and reduction of spontaneous glomerulonephritis and arthritis by orally administered NG-monomethyl-L-arginine.The Journal of experimental medicine · 1994
    Article

Corrections and comments

• Commented on by
  What are the types and cellular sources of free radicals in the pathogenesis of type 1 (insulin-dependent) diabetes mellitus?1993

Authors and funding

2 authors.

Funding

No grant is acknowledged in the PubMed record.

Abstract

PubMed holds no abstract for this paper.

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