ArticleCell and tissue research1992
Co-localization of vimentin and cytokeratins in M-cells of rabbit gut-associated lymphoid tissue (GALT).
Article in Cell and tissue research, 1992. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
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Who cites it
29 citing papers in PubMed, 77 citations in OpenAlex.
- Issues for patchy tissues: defining roles for gut-associated lymphoid tissue in neurodevelopment and disease.Journal of neural transmission (Vienna, Austria : 1996) · 2023Review
- Identifying human and murine M cells in vitro.Experimental biology and medicine (Maywood, N.J.) · 2019Review
- Molecular cloning, polymorphism, and expression analysis of the LKB1/STK11 gene and its association with non-specific digestive disorder in rabbits.Molecular and cellular biochemistry · 2018Article
- Characterization of New Zealand White Rabbit Gut-Associated Lymphoid Tissues and Use as Viral Oncology Animal Model.ILAR journal · 2016Article
- Roles of M cells in infection and mucosal vaccines.Human vaccines & immunotherapeutics · 2014Review
- C6, a new monoclonal antibody, reacts with the follicle-associated epithelium of calf ileal Peyer's patches.Journal of veterinary science · 2013Article
- Seven kinds of intermediate filament networks in the cytoplasm of polarized cells: structure and function.Acta histochemica et cytochemica · 2010Article
- The identification of intestinal M cells in the sacculus rotundus and appendix of the Angora rabbit.Veterinary research communications · 2010Article
- Keratin 20 expressed in the endocrine and exocrine cells of the rabbit duodenum.Acta histochemica et cytochemica · 2007Article
- Immunochemical, biomolecular and biochemical characterization of bovine epithelial intestinal primocultures.BMC cell biology · 2005Article
- Antigen transport into Peyer's patches: increased uptake by constant numbers of M cells.The American journal of pathology · 2004Article
- Vimentin-positive cells in the epithelium of rabbit ileal villi represent cup cells but not M-cells.The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society · 2003Article
- The viral sigma1 protein and glycoconjugates containing alpha2-3-linked sialic acid are involved in type 1 reovirus adherence to M cell apical surfaces.Journal of virology · 2003Article
- Vimentin, cytokeratin 8 and cytokeratin 18 are not specific markers for M-cells in human palatine tonsils.Journal of anatomy · 2001Article
- Peyer's patches epithelium in the rat: a morphological, immunohistochemical, and morphometrical study.Digestive diseases and sciences · 2001Article
- Review
- The development of M cells in Peyer's patches is restricted to specialized dome-associated crypts.The American journal of pathology · 1999Article
- Human intestinal M cells display the sialyl Lewis A antigen.Infection and immunity · 1999Article
- Mucin-related epitopes distinguish M cells and enterocytes in rabbit appendix and Peyer's patches.Infection and immunity · 1999Article
- Article
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The occurrence of cytokeratins, vimentin, and desmin in the dome epithelia and adjacent non-dome epithelia in four locations of gut-associated lymphoid tissues (GALT) of adult and newborn rabbits (Peyer's patches, sacculus rotundus, caecal lymphoid patches and appendix) was studied with monoclonal antibodies, using the indirect immunoperoxidase technique. In all locations investigated in adult animals, antibodies specific for vimentin labelled (1) M-cells, which engulf intra-epithelial lymphocytes, (2) columnar epithelial cells at the base of the domes lacking an apparent contact with lymphocytes ("immature" M-cells), and (3) flat cells, which lie in the lamina propria under the dome epithelium, and which line the basal lamina with thin cytoplasmic processes. In newborn rabbits, columnar epithelial cells resembling the immature M-cells of adults were selectively stained with vimentin antibodies. In M-cells, the strongest immunoreactivity was present in the perinuclear region and close to the pocket membrane, whereas the most apical and most basal parts of the cytoplasm showed no vimentin-immunoreactivity. Enterocytes in the dome epithelium and in the non-dome epithelium were vimentin-negative. M-cells and enterocytes bound antibodies against cytokeratin peptides 18 and 19 in adult and newborn animals. Compared with enterocytes, M-cells showed less intense staining for cytokeratins. Dome epithelia and no-dome epithelia did not contain desmin-immunoreactive cells. The results suggest that vimentin is a sensitive marker for M-cells in rabbit GALT.
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