ArticleImmunology1992
Characterization of the membrane attack complex inhibitory protein CD59 antigen on human amniotic cells and in amniotic fluid.
Article in Immunology, 1992. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
What it found
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Who cites it
26 citing papers in PubMed, 75 citations in OpenAlex.
- Coalescing nephron and ureteric bud progenitors potentiates nephrogenesis in recellularized kidney scaffolds.bioRxiv : the preprint server for biology · 2026Article
- Coagulation activation and hepatic engraftment of human amnion-derived cells after intraportal transplantation in rats.Regenerative medicine · 2025Article
- Stem cells and COVID-19: are the human amniotic cells a new hope for therapies against the SARS-CoV-2 virus?Stem cell research & therapy · 2021Review
- The Immunomodulatory Properties of Amniotic Cells: The Two Sides of the Coin.Cell transplantation · 2018Article
- Nuclear CD24 Drives Tumor Growth and Is Predictive of Poor Patient Prognosis.Cancer research · 2017Article
- A Rational Strategy for the Use of Amniotic Epithelial Stem Cell Therapy for Liver Diseases.Stem cells translational medicine · 2016Review
- Amniotic membrane in oral and maxillofacial surgery.Oral and maxillofacial surgery · 2014Review
- Functional regeneration of irradiated salivary glands with human amniotic epithelial cells transplantation.International journal of clinical and experimental pathology · 2013Article
- Amnion-derived stem cells: in quest of clinical applications.Stem cell research & therapy · 2011Review
- Ascitic complement system in ovarian cancer.British journal of cancer · 2005Article
- Cytolytic complement activity in otitis media with effusion.Clinical and experimental immunology · 2001Article
- Complement regulatory activity of normal human intraocular fluid is mediated by MCP, DAF, and CD59.Investigative ophthalmology & visual science · 2000Article
- Production and functional characterization of a soluble recombinant form of mouse CD59.Immunology · 2000Article
- Melanoma cells constitutively release an anchor-positive soluble form of protectin (sCD59) that retains functional activities in homologous complement-mediated cytotoxicity.The Journal of clinical investigation · 1997Article
- Complement regulatory protein expression by a human oligodendrocyte cell line: cytokine regulation and comparison with astrocytes.Immunology · 1996Article
- Human carcinomas variably express the complement inhibitory proteins CD46 (membrane cofactor protein), CD55 (decay-accelerating factor), and CD59 (protectin).The American journal of pathology · 1996Article
- Structural composition and functional characterization of soluble CD59: heterogeneity of the oligosaccharide and glycophosphoinositol (GPI) anchor revealed by laser-desorption mass spectrometric analysis.The Biochemical journal · 1996Article
- Article
- Shedding and enrichment of the glycolipid-anchored complement lysis inhibitor protectin (CD59) into milk fat globules.Immunology · 1995Article
- Enhanced complement susceptibility of avidin-biotin-treated human erythrocytes is a consequence of neutralization of the complement regulators CD59 and decay accelerating factor.The Biochemical journal · 1995Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
A functional complement system and the potential for its activation are present in human amniotic fluid. We have recently demonstrated that CD59 antigen is present and functionally active on human amniotic epithelial cells (HAEC). We have now further examined the role of this protein on HAEC and have also demonstrated its presence in amniotic fluid (AF). CD59 Ag on HAEC is similar in size to the erythrocyte protein and is anchored via glycosyl phosphatidylinositol. The AF protein retained the capacity to incorporate into target cells and protect against lysis by complement. These data suggest that HAEC secrete into AF a form of CD59 Ag which retains inhibitory activity and which may be important in protection of the foetus from maternal complement in utero.
Indexed as
Identifiers
1383132PMC1421564W137654459What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.