Evidence map›Paper›PMID 1383026›Full record

ReviewEuropean journal of epidemiology1992

Cytological immunodetection of yeast glycoprotein secretion.

J C Cailliez, D Poulain, D W Mackenzie, L Polonelli

Abstract readReview
PubMed Publisher
In one paragraph

Review in European journal of epidemiology, 1992. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.6field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 6 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 2 countries.

J C CailliezUnité 42 INSERM, Domaine du CERTIA, Villeneuve d'Ascq, France.
D Poulain
D W Mackenzie
L Polonelli
Centre d'Études et de Recherches sur les Qualifications · FRInserm · FRUniversity of Parma · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Expression of antigenic epitopes shared by secreted yeast glycoproteins was studied using specific immunological probes. Application of cytological and ultrastructural methods of immunodetection, employing monoclonal antibodies, permitted us to localize these glycoproteins in the cytoplasm, through the cell wall and at the yeast cell surface. Importance of glycosylation-secretion relationships were evaluated in the secretion process of these molecules. The cell wall crossing and the cell surface distribution of antigenic glycoproteins was described in immunoelectron microscopy and immunofluorescence. Some preferential secretion "ways" were suspected through the yeast cell wall leading to an heterogenous distribution of cell surface glycoproteins destined to be excreted into the medium. Antigenic variability of cell wall glycoproteins expression was discussed in relation with the glycoprotein secretion.

Indexed as

Antibodies, MonoclonalAntigenic VariationBiological Transport, ActiveEpitopesFluorescent Antibody TechniqueGlycosylationMembrane GlycoproteinsMicroscopy, ImmunoelectronSaccharomyces cerevisiaeAntibodies, MonoclonalEpitopesMembrane Glycoproteins

Identifiers

PMID1383026
OpenAlexW2031646455

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.