Evidence map›Paper›PMID 1381302›Full record

ArticleClinical and experimental immunology1992

Hepatitis C: a possible etiology for cryoglobulinaemia type II.

A Pechère-Bertschi, L Perrin, P de Saussure, J J Widmann, E Giostra, J A Schifferli

Open access · bronzeAbstract read
In one paragraph

Article in Clinical and experimental immunology, 1992. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
4.5field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 63 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Review
  5. Cryoglobulins in chronic hepatitis C virus infection.Clinical and experimental immunology · 2003
    Review
  6. Cryoglobulins are not essential.Annals of the rheumatic diseases · 1998
    Article
  7. Mixed cryoglobulinemia as a model of systemic vasculitis.Clinical reviews in allergy & immunology · 1997
    Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

A Pechère-BertschiDepartment of Medicine, Hôpital Cantonal Universitaire, Geneva, Switzerland.
L Perrin
P de Saussure
J J Widmann
E Giostra
J A Schifferli
Hôpital Nestlé · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Out of 15 successive patients with mixed essential cryoglobulinaemia type II (monoclonal IgM kappa/IgG), 13 had serological evidence for hepatitis C infection as shown by specific enzyme immunoassays and immunoblot. RNA was purified from the serum of seven patients and hepatitis C sequences were identified in five following reverse transcription and DNA amplification. The liver histology showed chronic active hepatitis with or without cirrhosis in the 12 patients with hepatitis C who had a liver biopsy. The two patients without serological evidence of hepatitis C suffered from haematological malignancies. Hepatitis C may be a major etiological agent of cryoglobulinaemia type II.

Indexed as

AdultAgedBase SequenceCryoglobulinemiaFemaleGene AmplificationHepacivirusHepatitis AntibodiesHepatitis CHepatitis C AntibodiesHepatitis, ChronicHumansImmunoblottingLiverLiver CirrhosisLiver Function TestsHepatitis AntibodiesHepatitis C AntibodiesRNA-Directed DNA PolymeraseTransaminases

Identifiers

PMID1381302
PMCPMC1554477
OpenAlexW1963896609

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.