ReviewJournal of bioenergetics and biomembranes1992
Toward the molecular structure of the mitochondrial channel, VDAC.
Review in Journal of bioenergetics and biomembranes, 1992. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
47 citing papers in PubMed.
- Dysfunction of Mitochondria in Alzheimer's Disease: ANT and VDAC Interact with Toxic Proteins and Aid to Determine the Fate of Brain Cells.International journal of molecular sciences · 2022Review
- Voltage-Dependent Anion Selective Channel 3: Unraveling Structural and Functional Features of the Least Known Porin Isoform.Frontiers in physiology · 2021Review
- NMR Spectroscopic Studies of Ion Channels in Lipid Bilayers: Sample Preparation Strategies Exemplified by the Voltage Dependent Anion Channel.Methods in molecular biology (Clifton, N.J.) · 2021Article
- Regulation of Single-Channel Conductance of Voltage-Dependent Anion Channel by Mercuric Chloride in a Planar Lipid Bilayer.The Journal of membrane biology · 2020Article
- Nanopore Fabrication and Application as Biosensors in Neurodegenerative Diseases.Critical reviews in biomedical engineering · 2020Review
- Adrenal Mitochondria and Steroidogenesis: From Individual Proteins to Functional Protein Assemblies.Frontiers in endocrinology · 2016Review
- A panoramic overview of mitochondria and mitochondrial redox biology.Toxicological research · 2014Article
- Voltage-dependent anion channels modulate mitochondrial metabolism in cancer cells: regulation by free tubulin and erastin.The Journal of biological chemistry · 2013Article
- VDAC structure, selectivity, and dynamics.Biochimica et biophysica acta · 2012Review
- Molecular dynamics studies of ion permeation in VDAC.Biophysical journal · 2011Article
- Free tubulin modulates mitochondrial membrane potential in cancer cells.Cancer research · 2010Article
- Orientation determination of interfacial beta-sheet structures in situ.The journal of physical chemistry. B · 2010Article
- Phosphorylation by Nek1 regulates opening and closing of voltage dependent anion channel 1.Biochemical and biophysical research communications · 2010Article
- Mini review on the structure and supramolecular assembly of VDAC.Journal of bioenergetics and biomembranes · 2008Review
- Regulation of hexokinase binding to VDAC.Journal of bioenergetics and biomembranes · 2008Review
- Structure of the voltage dependent anion channel: state of the art.Journal of bioenergetics and biomembranes · 2008Review
- Glucose phosphorylation and mitochondrial binding are required for the protective effects of hexokinases I and II.Molecular and cellular biology · 2008Article
- Phosphorothioate oligonucleotides block the VDAC channel.Biophysical journal · 2007Article
- NMR structural investigation of the mitochondrial outer membrane protein VDAC and its interaction with antiapoptotic Bcl-xL.Biochemistry · 2007Article
- The voltage-dependent anion channel, a major component of the tRNA import machinery in plant mitochondria.Proceedings of the National Academy of Sciences of the United States of America · 2006Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
A summary is presented of the most recent information about the structure and mechanism of closure of the mitochondrial channel, VDAC. Considerable information has come from studies involving electron microscopy of two-dimensional crystals and from electrophysiological studies of wild-type channels and site-directed mutants. Available evidence points to a beta-barrel as the basic structural model for VDAC. Two models for voltage- or effector- induced closure have been proposed, the first involving removal of strands from the wall of the pore, the second invoking movement of protein domains into the lumen. Experimental strategies to resolve the actual mechanism are presented.
Indexed as
Identifiers
1380507What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.