ArticleThe Journal of membrane biology1992
IP3- and cAMP-induced responses in isolated olfactory receptor neurons from the channel catfish.
Article in The Journal of membrane biology, 1992. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed, 80 citations in OpenAlex.
- Catfishes: A global review of the literature.Heliyon · 2023Review
- Phosphoinositide and Erk signaling pathways mediate activity-driven rodent olfactory sensory neuronal survival and stress mitigation.Journal of neurochemistry · 2015Article
- Increases in intracellular calcium via activation of potentially multiple phospholipase C isozymes in mouse olfactory neurons.Frontiers in cellular neuroscience · 2014Article
- Activation state of the M3 muscarinic acetylcholine receptor modulates mammalian odorant receptor signaling.Science signaling · 2011Article
- Odorant responsiveness of squid olfactory receptor neurons.Anatomical record (Hoboken, N.J. : 2007) · 2008Article
- Vomeronasal sensory neurons from Sternotherus odoratus (stinkpot/musk turtle) respond to chemosignals via the phospholipase C system.The Journal of experimental biology · 2006Article
- Correlation between olfactory receptor cell type and function in the channel catfish.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2003Article
- Peripheral odor coding in the rat and frog: quality and intensity specification.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2000Article
- Characterization of inositol-1,4,5-trisphosphate-gated channels in the plasma membrane of rat olfactory neurons.Biophysical journal · 1999Article
- OSM-9, a novel protein with structural similarity to channels, is required for olfaction, mechanosensation, and olfactory adaptation in Caenorhabditis elegans.The Journal of neuroscience : the official journal of the Society for Neuroscience · 1997Article
- Odor discrimination of "IP3-" and "cAMP-increasing" odorants in the turtle olfactory bulb.Pflugers Archiv : European journal of physiology · 1996Article
- Gated conductances in native and reconstituted membranes from frog olfactory cilia.Biophysical journal · 1996Article
- Cyclic nucleotide- and inositol phosphate-gated ion channels in lobster olfactory receptor neurons.Proceedings of the National Academy of Sciences of the United States of America · 1994Article
- Deflagellation of Chlamydomonas reinhardtii follows a rapid transitory accumulation of inositol 1,4,5-trisphosphate and requires Ca2+ entry.The Journal of cell biology · 1993Article
- Human olfactory neurons respond to odor stimuli with an increase in cytoplasmic Ca2+.Biophysical journal · 1993Article
- Contribution of the ciliary cyclic nucleotide-gated conductance to olfactory transduction in the salamander.The Journal of physiology · 1993Article
- Protein kinase C sensitizes olfactory adenylate cyclase.The Journal of general physiology · 1993Article
- The cyclic nucleotide-activated conductance in olfactory cilia: effects of cytoplasmic Mg2+ and Ca2+.The Journal of membrane biology · 1993Article
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
Abstract
Olfactory receptor neurons enzymatically dissociated from channel catfish olfactory epithelium were depolarized transiently following dialysis of IP3 or cAMP (added to the patch pipette) into the cytoplasm. Voltage and current responses to IP3 were blocked by ruthenium red, a blocker of an IP3-gated Ca(2+)-release channel in sarcoplasmic reticulum. In contrast, the responses to cAMP were not blocked by extracellularly applied ruthenium red, nor by L-cis-diltiazem or amiloride and two of its derivatives. The current elicited by cytoplasmic IP3 in neurons under voltage clamp displayed a voltage dependence different from that of the cAMP response which showed marked outward rectification. A sustained depolarization was caused by increased cytoplasmic IP3 or cAMP when the buffering capacity for Ca2+ of the pipette solution was increased, when extracellular Ca2+ was removed or after addition of 20-200 nM charybdotoxin to the bathing solution, indicating that the repolarization was caused by an increase in [Cai] that opened Ca(2+)-activated K+ channels. The results suggest that different conductances modulated by either IP3 or cAMP are involved in mediating olfactory transduction in catfish olfactory receptor neurons and that Ca(2+)-activated K+ channels contribute to the termination of the IP3 and cAMP responses.
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