ArticleProceedings of the National Academy of Sciences of the United States of America1992
Two types of anion channel currents in guard cells with distinct voltage regulation.
Article in Proceedings of the National Academy of Sciences of the United States of America, 1992. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 95 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
95 citing papers in PubMed, 262 citations in OpenAlex.
- Guard cell signal transduction mechanisms controlling stomatal movements by light, abscisic acid, CO2, VPD and heat.Plant physiology · 2026Review
- SlSLAH2 mediates malate exudation and contributes to aluminum tolerance.Nature communications · 2026Article
- Structural insights into the coordinated regulation of the SLAH family in Arabidopsis thaliana.Nature communications · 2025Article
- Mechanistic insights into phosphoactivation of SLAC1 in guard cell signaling.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- A charged existence: A century of transmembrane ion transport in plants.Plant physiology · 2024Review
- Molecular response and evolution of plant anion transport systems to abiotic stress.Plant molecular biology · 2022Review
- Plant hormone regulation of abiotic stress responses.Nature reviews. Molecular cell biology · 2022Review
- Evolution of long-distance signalling upon plant terrestrialization: comparison of action potentials in Characean algae and liverworts.Annals of botany · 2022Review
- Structure of the Arabidopsis guard cell anion channel SLAC1 suggests activation mechanism by phosphorylation.Nature communications · 2022Article
- Cryo-EM structure and electrophysiological characterization of ALMT fromScience advances · 2022Article
- Inferring the genetic responses to acute drought stress across an ecological gradient.BMC genomics · 2022Article
- Structural and Functional Insights into the Role of Guard Cell Ion Channels in Abiotic Stress-Induced Stomatal Closure.Plants (Basel, Switzerland) · 2021Review
- Differential regulation of drought stress by biological membrane transporters and channels.Plant cell reports · 2021Review
- Membrane voltage as a dynamic platform for spatiotemporal signaling, physiological, and developmental regulation.Plant physiology · 2021Article
- Potassium Control of Plant Functions: Ecological and Agricultural Implications.Plants (Basel, Switzerland) · 2021Article
- Ethylene and Sulfur Coordinately Modulate the Antioxidant System and ABA Accumulation in Mustard Plants under Salt Stress.Plants (Basel, Switzerland) · 2021Article
- Early Cellular Responses Induced by Sedimentary Calcite-Processed Particles in Bright Yellow 2 Tobacco Cultured Cells.International journal of molecular sciences · 2020Article
- Engineering energetically efficient transport of dicarboxylic acids in yeastProceedings of the National Academy of Sciences of the United States of America · 2019Article
- The malate-activated ALMT12 anion channel in the grassThe Journal of biological chemistry · 2019Article
- Guard Cell Membrane Anion Transport Systems and Their Regulatory Components: An Elaborate Mechanism Controlling Stress-Induced Stomatal Closure.Plants (Basel, Switzerland) · 2019Review
35 more citing papers are in PubMed but not listed here.
Corrections and comments
- Erratum issued
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Transpirational water loss by plants is reduced by closing of stomatal pores in the leaf epidermis. Anion channels in the plasma membrane of guard cells may provide a key molecular mechanism for control of stomatal closing in leaves. However, central questions regarding the regulation, diversity, and function of anion channels in guard cells and other higher plant cells remain unanswered. We show here that two highly distinct types of depolarization-activated anion currents operate in the plasma membrane of Vicia faba guard cells. One described type of anion channel was activated rapidly within 50 ms by depolarization, inactivated during prolonged stimulation, and deactivated rapidly at hyperpolarized potentials (R-type anion current). The other depolarization-activated anion current showed extremely slow voltage-dependent activation and deactivation (S-type anion current) and lacked inactivation. The distinct voltage and time dependencies of R-type and S-type anion channels suggest that they may play a role during depolarization-associated signal transduction in higher plant cells and that these anion channels may contribute to different processes in the regulation of stomatal movements. In particular, the slow and sustained nature of S-type anion channel activation revealed here leads us to hypothesize that S-type anion channels may provide a central molecular mechanism for control of stomatal closing, which is accompanied by long-term anion efflux and depolarization.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.