ArticleImmunology1992
CD4+ T cells are required for antigen-specific recruitment of neutrophils by BCG-immune spleen cells.
Article in Immunology, 1992. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
9 citing papers in PubMed, 17 citations in OpenAlex.
- Article
- Article
- T helper 17-associated cytokines are produced during antigen-specific inflammation in the mammary gland.PloS one · 2013Article
- Tumour necrosis factor-alpha and leukotriene B(4) mediate the neutrophil migration in immune inflammation.British journal of pharmacology · 2001Article
- Inflammatory response following intranasal infection with Mycobacterium avium complex: role of T-cell subsets and gamma interferon.Infection and immunity · 1995Article
- The role of lymphocytes in the neutrophil migration induced by ovalbumin in immunized rats.Immunology · 1995Article
- Neutrophils as effector cells of T-cell-mediated, acquired immunity in murine listeriosis.Immunology · 1994Article
- Interferon-gamma (IFN-gamma) and macrophage inflammatory proteins (MIP)-1 and -2 are involved in the regulation of the T cell-dependent chronic peritoneal neutrophilia of mice infected with mycobacteria.Clinical and experimental immunology · 1992Article
- T cell regulation of the chronic peritoneal neutrophilia during mycobacterial infections.Clinical and experimental immunology · 1992Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Mycobacterium bovis bacillus Calmette-Guérin (BCG)-immune spleen cells co-inoculated into the peritoneal cavity of normal mice with BCG sonicate protein as antigen could induce an antigen-specific recruitment of neutrophils, dependent on the antigen dose and cell number. This response was significantly reduced by anti-T lymphocyte and anti-CD4 treatment of the immune spleen cells prior to the inoculation. Removal of adherent or phagocytic cells or lysis of B cells, had no significant effect. Killing of dividing cells in the splenic population induced a slight reduction in the ability of spleen cells to recruit neutrophils. M. avium sonicate protein was also able to induce BCG-immune spleen cells to mobilize neutrophils but bovine serum albumin, Listeria monocytogenes cytosolic protein and 65,000 MW heat shock protein were not. These results show that CD4+ T cells are able to induce neutrophil recruitment in an antigen-specific way during a mycobacterial infection.
Indexed as
Identifiers
1374053PMC1384733W94906444What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.