ArticleGenetics1992
Sequence heterogeneity between the two genes encoding 16S rRNA from the halophilic archaebacterium Haloarcula marismortui.
Article in Genetics, 1992. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 65 papers.
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Who cites it
65 citing papers in PubMed, 198 citations in OpenAlex.
- Investigating Additive and Replacing Horizontal Gene Transfers Using Phylogenies and Whole Genomes.Genome biology and evolution · 2024Article
- The Archaeal Transcription Termination Factor aCPSF1 is a Robust Phylogenetic Marker for Archaeal Taxonomy.Microbiology spectrum · 2021Article
- Nutrient supplementation experiments with saltern microbial communities implicate utilization of DNA as a source of phosphorus.The ISME journal · 2021Article
- Orthogonal translation enables heterologous ribosome engineering in E. coli.Nature communications · 2021Article
- Temperature-dependent expression of different guanine-plus-cytosine content 16S rRNA genes in Haloarcula strains of the class Halobacteria.Antonie van Leeuwenhoek · 2019Article
- Metal Transformation by a NovelFrontiers in microbiology · 2018Article
- Comparative RNA function analysis reveals high functional similarity between distantly related bacterial 16 S rRNAs.Scientific reports · 2017Article
- Highly divergent 16S rRNA sequences in ribosomal operons of Scytonema hyalinum (Cyanobacteria).PloS one · 2017Article
- Phylogenetic Network Analysis Revealed the Occurrence of Horizontal Gene Transfer of 16S rRNA in the GenusFrontiers in microbiology · 2017Article
- Analysis of the bacteriorhodopsin-producing haloarchaea reveals a core community that is stable over time in the salt crystallizers of Eilat, Israel.Extremophiles : life under extreme conditions · 2016Article
- Intragenomic polymorphism and intergenomic recombination in the ribosomal RNA genes of strains belonging to a yeast speciesMycology · 2016Article
- Rare Events of Intragenus and Intraspecies Horizontal Transfer of the 16S rRNA Gene.Genome biology and evolution · 2015Article
- Article
- Type material in the NCBI Taxonomy Database.Nucleic acids research · 2015Article
- Lateral transfer of eukaryotic ribosomal RNA genes: an emerging concern for molecular ecology of microbial eukaryotes.The ISME journal · 2014Article
- Diverse antimicrobial interactions of halophilic archaea and bacteria extend over geographical distances and cross the domain barrier.MicrobiologyOpen · 2013Article
- Intragenomic heterogeneity of 16S rRNA genes causes overestimation of prokaryotic diversity.Applied and environmental microbiology · 2013Article
- Variable copy number, intra-genomic heterogeneities and lateral transfers of the 16S rRNA gene in Pseudomonas.PloS one · 2012Article
- Quantifying homologous replacement of loci between haloarchaeal species.Genome biology and evolution · 2012Article
- Diversity of 16S rRNA genes within individual prokaryotic genomes.Applied and environmental microbiology · 2010Article
5 more citing papers are in PubMed but not listed here.
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2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The halophilic archaebacterium, Haloarcula marismortui, contains two nonadjacent ribosomal RNA operons, designated rrnA and rrnB, in its genome. The 16S rRNA genes within these operons are 1472 nucleotides in length and differ by nucleotide substitutions at 74 positions. The substitutions are not uniformly distributed but rather are localized within three domains of 16S rRNA; more than two-thirds of the differences occur within the domain bounded by nucleotides 508 and 823. This domain is known to be important for P site binding of aminoacylated tRNA and for 30-50S subunit association. Using S1 nuclease protection, it has been shown that the 16S rRNAs transcribed from both operons are equally represented in the functional 70S ribosome population. Comparison of these two H. marismortui sequences to the 16S gene sequences from related halophilic genera suggests that (i) in diverging genera, mutational differences in 16S gene sequences are not clustered but rather are more generally distributed throughout the length of the 16S sequence, and (ii) the rrnB sequence, particularly within the 508-823 domain, is more different from the out group sequences than is the rrnA sequence. Several possible explanations for the evolutionary origin and maintenance of this sequence heterogeneity within 16S rRNA of H. marismortui are discussed.
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