ArticleJournal of clinical microbiology1992
Isolation and characterization of two distinct human rotavirus strains with G6 specificity.
Article in Journal of clinical microbiology, 1992. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 63 papers.
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Who cites it
63 citing papers in PubMed, 160 citations in OpenAlex.
- Hidden Circulation and Socio-Sanitary Vulnerability: Rotavirus A and Human Adenovirus Prevalence in Symptomatic and Asymptomatic Children in Central Brazil Post-COVID-19.Pathogens (Basel, Switzerland) · 2025Article
- Genetic diversity of rotavirus A in Argentina during 2019-2022: detection of G6 strains and insights regarding its dissemination.Archives of virology · 2023Article
- Rotavirus A during the COVID-19 Pandemic in Brazil, 2020-2022: Emergence of G6P[8] Genotype.Viruses · 2023Article
- A Multiplex PCR/LDR Assay for Viral Agents of Diarrhea with the Capacity to Genotype Rotavirus.Scientific reports · 2018Article
- Detection of the first G6P[14] human rotavirus strain in an infant with diarrhoea in Ghana.Virology journal · 2016Article
- Continuous detection and genetic diversity of human rotavirus A in sewage in eastern China, 2013-2014.Virology journal · 2016Article
- Molecular epidemiology of rotavirus in cats in the United Kingdom.Journal of clinical microbiology · 2015Article
- Article
- Identification by full-genome analysis of a bovine rotavirus transmitted directly to and causing diarrhea in a human child.Journal of clinical microbiology · 2013Article
- Detection and full genomic analysis of G6P[9] human rotavirus in Japan.Virus genes · 2011Article
- Intestinal epithelia activate anti-viral signaling via intracellular sensing of rotavirus structural components.Mucosal immunology · 2010Article
- The global spread of rotavirus G10 strains: Detection in Ghanaian children hospitalized with diarrhea.The Journal of infectious diseases · 2010Article
- Europe, the bull and the Minotaur: the biological legacy of a Neolithic love story.Environmental microbiology · 2009Review
- Are human P[14] rotavirus strains the result of interspecies transmissions from sheep or other ungulates that belong to the mammalian order Artiodactyla?Journal of virology · 2009Article
- Diversity in Indian equine rotaviruses: identification of genotype G10,P6[1] and G1 strains and a new VP7 genotype (G16) strain in specimens from diarrheic foals in India.Journal of clinical microbiology · 2007Article
- Molecular characterization of novel G5 bovine rotavirus strains.Journal of clinical microbiology · 2006Article
- Full genomic analysis of human rotavirus strain B4106 and lapine rotavirus strain 30/96 provides evidence for interspecies transmission.Journal of virology · 2006Article
- Crystallization and preliminary X-ray diffraction analysis of the sialic acid-binding domain (VP8*) of porcine rotavirus strain CRW-8.Acta crystallographica. Section F, Structural biology and crystallization communications · 2005Article
- Molecular characterizations of human and animal group a rotaviruses in the Netherlands.Journal of clinical microbiology · 2005Article
- Eight-year survey of human rotavirus strains demonstrates circulation of unusual G and P types in Hungary.Journal of clinical microbiology · 2004Article
3 more citing papers are in PubMed but not listed here.
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Authors and funding
8 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Two new human rotavirus (HRV) strains, PA151 and PA169, with subgroup I specificity and a long RNA pattern, yet with a serotype G (VP7) specificity different from those of any of the six well-established HRV serotypes (G1 to G4, G8, and G9), were isolated 3 months apart from two children with acute gastroenteritis in Sicily, southern Italy, in the winter season of 1987 and 1988. The HRV isolates were adapted to growth in cell cultures and were then characterized by neutralization and RNA-RNA (Northern blot) hybridization. Cross-neutralization studies with type-specific immune sera to RV serotypes 1 to 10 showed the antigenic relatedness of the two strains with serotype 6 bovine strains UK and NCDV. Monoclonal antibodies to VP7 of UK were able to recognize UK and NCDV strains as well as both HRV isolates. Cross-hybridization studies showed a genetic relatedness of PA151 and PA169 to bovine strains for all genes except gene 4. Gene 4 of PA151 appeared to be genetically related to that of AU228 (a human strain of subgroup I and with serotype G3 specificity that belongs to a feline genogroup), whereas gene 4 of PA169 appeared to be unique, yet it was related to gene 4 of two recently reported subgroup I HRV strains, one (PA710) with serotype G3 specificity and the other (HAL1271) with serotype G8 specificity. The new HRV strains must be taken into consideration when deciding strategies for the development of an effective RV vaccine.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.