Evidence map›Paper›PMID 13680035›Full record

ArticleEuropean journal of clinical pharmacology2003

Inappropriate use of anti-asthmatic drugs in the Italian paediatric population.

Antonio Clavenna, Elisa Rossi, Alessandra Berti, Giorgio Pedrazzi, Marisa De Rosa, Maurizio Bonati, ARNO Working Group

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Article in European journal of clinical pharmacology, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
1.8field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 36 citations in OpenAlex.

  1. Pooled it
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  11. Prevalence of chronic obstructive pulmonary disease and pattern of comorbidities in a general population.International journal of chronic obstructive pulmonary disease · 2007
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Antonio ClavennaLaboratory for Mother and Child Health, Mario Negri Institute for Pharmacological Research, Milan, Italy. clavenna@marionegri.it
Elisa Rossi
Alessandra Berti
Giorgio Pedrazzi
Marisa De Rosa
Maurizio Bonati
ARNO Working Group
Mario Negri Institute for Pharmacological Research · ITCineca · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo evaluate anti-asthmatic drug prescriptions in a large Italian paediatric population.

methodsPrescriptions involving 417,559 children younger than 14 years old dispensed during 2000 by the retail pharmacies of 17 Italian local health units participating in the ARNO project were analysed.

resultsIn the study, 92,890 children (22.2%) received at least one anti-asthmatic drug prescription. The prevalence of prescriptions was higher in children less than 1 year old, significantly decreased with increasing age, and was higher in boys than in girls. Of children treated with anti-asthmatic drugs, 71.5% received prescriptions of less than three boxes. Beclomethasone, salbutamol, flunisolide and fluticasone were the most prescribed drugs. Beclomethasone and flunisolide were prescribed mostly as nebulised suspension.

conclusionsThe data suggest that anti-asthmatic drugs are often prescribed for diseases different from asthma and that many children are exposed to treatments for which there is no evidence of efficacy.

Indexed as

Anti-Asthmatic AgentsChildChild, PreschoolDatabases, FactualDrug PrescriptionsDrug Utilization ReviewFemaleHumansInfantItalyMaleAnti-Asthmatic Agents

Identifiers

PMID13680035
OpenAlexW1975262476

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.