Evidence map›Paper›PMID 13679855›Full record

ArticleOncogene2003

Development of CD30+ lymphoproliferative disease in mice lacking interferon regulatory factor-1.

Donna D Eason, Cynthia LeBron, Domenico Coppola, Lynn C Moscinski, Sandra Livingston, E Truitt Sutton, George Blanck

Open access · bronzeAbstract readComparative Study
PubMed Publisher
In one paragraph

Article in Oncogene, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Donna D EasonDepartment of Biochemistry and Molecular Biology, College of Medicine, University of South Florida, Tampa, FL 33612, USA.
Cynthia LeBron
Domenico Coppola
Lynn C Moscinski
Sandra Livingston
E Truitt Sutton
George Blanck
University of South Florida · USMoffitt Cancer Center · US

Funding

INTERFERON REGULATORY FACTOR 2 FUNCTIONSR01CA081497 · NCI · UNIVERSITY OF SOUTH FLORIDA · PI BLANCK, GEORGE · 1999 to 2002
$598k
NCI NIH HHS R01-CA81497
6 · The paper itself

Abstract

Human lymphomas continue to represent a major challenge in oncology, and in particular occur at very high frequencies in AIDS patients. We report here the development of a CD30+ lymphoproliferative disease in mice lacking the proapoptotic transcription factor, interferon regulatory factor-1. These mice most closely represent a model of human anaplastic large-cell lymphoma (ALCL). This mouse model of lymphoma will likely be useful in understanding the development of ALCL and in understanding the development of other closely related CD30+ forms of lymphoma, such as CD30+ Hodgkin's disease and CD30+ cutaneous T-cell lymphoma. This mouse model will also be useful in testing therapies for different forms of CD30+ lymphoma, in particular anti-CD30-based therapies.

Indexed as

AnimalsDNA-Binding ProteinsImmunohistochemistryInterferon Regulatory Factor-1Ki-1 AntigenLymphatic DiseasesLymph NodesLymphoma, Large-Cell, AnaplasticLymphoproliferative DisordersMiceMice, KnockoutPhosphoproteinsRetinoblastoma ProteinTime FactorsTranscription FactorsDNA-Binding ProteinsInterferon Regulatory Factor-1Irf1 protein, mouseKi-1 AntigenPhosphoproteinsRetinoblastoma ProteinTranscription Factors

Identifiers

PMID13679855
OpenAlexW2124341418

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.