Evidence map›Paper›PMID 13677271›Full record

ReviewWiener klinische Wochenschrift2003

Diagnostic and prognostic value of colony formation of hematopoietic progenitor cells in myeloid malignancies.

Leopold Ohler, Klaus Geissler, Wolfgang Hinterberger

Abstract readComparative StudyReview
PubMed Publisher
In one paragraph

Review in Wiener klinische Wochenschrift, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Leopold OhlerDivision of Hematology, Department of Internal Medicine I, University of Vienna, Vienna, Austria. leopold.oehler@akh-wien.ac.at
Klaus Geissler
Wolfgang Hinterberger

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hematopoietic progenitor cells are capable of forming colonies of mature blood cells in semisolid media in response to specific growth factors. Colony assays have been extensively used for many years to study normal and malignant hematopoiesis in vitro. In fact, these assays have provided an excellent research tool for investigating growth and differentiation of progenitor cells in response to positive and negative regulators of hematopoiesis. However, apart from their role in basic research, colony assays are also widely used in routine clinical practice in the diagnosis of various hematologic disorders, such as aplastic anemia, myelodysplastic syndromes and myeloproliferative disorders. This review summarizes our current knowledge on the diagnostic value and prognostic significance of the growth of progenitor cells in peripheral blood and bone marrow in patients with myeloid malignancies.

Indexed as

Colony-Forming Units AssayHematopoietic Stem CellsAcute DiseaseAnemia, AplasticHumansLeukemia, Myelogenous, Chronic, BCR-ABL PositiveLeukemia, MyeloidMyelodysplastic SyndromesMyeloproliferative DisordersPolycythemia VeraPrimary MyelofibrosisPrognosisThrombocytosis

Identifiers

PMID13677271

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.