Evidence map›Paper›PMID 1362197›Full record

ArticleThe Histochemical journal1992

The expression of CD15 in dissociated cultured rat dorsal root ganglion cells.

E Marani, M Deenen, J A Maassen

Abstract read
PubMed Publisher
In one paragraph

Article in The Histochemical journal, 1992. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 97% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 5 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

E MaraniNeuroregulation Group, Leiden University, The Netherlands.
M Deenen
J A Maassen
Leiden University · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study describes the presence of CD15 in dorsal root ganglia neurons in five experimental conditions: chemically defined medium and the same medium with added nerve growth factor, retinoic acid or antibodies against insulin or tyrosine phosphate. Positive astrocyte controls were used to differentiate the monoclonal antibodies that did not react with CD15. Those monoclonal antibodies which detected CD15 in this positive control were also used to study CD15 positivity in dorsal root ganglion cells. This study shows: (i) masking of the CD15 antibody, which influences the detection capacity of the monoclonal antibodies used; (ii) that CD15 discerns two subpopulations of DRG neurons: a CD15-positive and a CD15-negative population; (iii) that CD15 expression is not involved in the outgrowth of protrusions or the wrapping by non-neuronal cells of DRG neurons.

Indexed as

AnimalsAntibodies, MonoclonalAntigens, CDAstrocytesCell AggregationCells, CulturedCell SeparationFemaleGanglia, SpinalLewis X AntigenPregnancyRatsRats, WistarAntibodies, MonoclonalAntigens, CDLewis X Antigen

Identifiers

PMID1362197
OpenAlexW1971454383

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.