ArticleMammalian genome : official journal of the International Mammalian Genome Society1992
Genetic mapping of the murine gene and 14 related sequences encoding chromosomal protein HMG-14.
Article in Mammalian genome : official journal of the International Mammalian Genome Society, 1992. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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10 citing papers in PubMed, 18 citations in OpenAlex.
- Evolution of high mobility group nucleosome-binding proteins and its implications for vertebrate chromatin specialization.Molecular biology and evolution · 2015Article
- Species-specific class I gene expansions formed the telomeric 1 mb of the mouse major histocompatibility complex.Genome research · 2003Article
- Mapping of the mouse Tdgf1 gene and Tdgf pseudogenes.Mammalian genome : official journal of the International Mammalian Genome Society · 1997Article
- Homologs of genes and anonymous loci on human chromosome 13 map to mouse chromosomes 8 and 14.Mammalian genome : official journal of the International Mammalian Genome Society · 1995Article
- Chromosome mapping of nine tropomyosin-related sequences in mice.Mammalian genome : official journal of the International Mammalian Genome Society · 1995Article
- Identification and genetic mapping of 151 dispersed members of 16 ribosomal protein multigene families in the mouse.Mammalian genome : official journal of the International Mammalian Genome Society · 1994Article
- Phosphoglycerate kinase pseudogenes in the tammar wallaby and other macropodid marsupials.Mammalian genome : official journal of the International Mammalian Genome Society · 1994Article
- Glycogen synthase: a putative locus for diet-induced hyperglycemia.The Journal of clinical investigation · 1994Article
- Molecular cloning, expression analysis, and chromosomal localization of mouse Hmg1-containing sequences.Mammalian genome : official journal of the International Mammalian Genome Society · 1994Article
- Identification and genetic mapping of the murine gene and 20 related sequences encoding chromosomal protein HMG-17.Mammalian genome : official journal of the International Mammalian Genome Society · 1993Article
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4 authors at 2 institutions in 1 country.
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Abstract
The high-mobility-group chromosomal protein HMG-14 preferentially binds to nucleosomal core particles of mammalian chromatin and may modulate the chromatin configuration of transcriptionally active genes. The human gene for HMG-14 has been localized to the Down syndrome region of Chromosome (Chr) 21 and may be involved in the etiology of this syndrome. Here we show, by means of genetic linkage analysis of interspecific and intersubspecific backcross mice, that the murine functional gene, Hmg14, is located on the distal end of mouse Chr 16, a region known to have conserved synteny with human Chr 21. In addition to the functional gene for HMG-14, both human and mouse genomes contain many related sequences that are probably processed pseudogenes. Here we map the locations of 14 Hmg14-related sequences in two mouse genomes. The 14 mapped loci are widely dispersed on ten chromosomes (Chrs 3, 5, 7, 9, 11, 12, 16, 17, 19, and X) and can be detected efficiently with a single cDNA probe. Thus, the Hmg14 multigene family is well suited to serve as genetic markers for other linkage studies in mice.
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