ArticleProceedings of the National Academy of Sciences of the United States of America1992
Glutamate receptors of Drosophila melanogaster: cloning of a kainate-selective subunit expressed in the central nervous system.
Article in Proceedings of the National Academy of Sciences of the United States of America, 1992. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed, 69 citations in OpenAlex.
- Tunable AMPA receptor function via recurrent evolution of heterotetramers.The Journal of general physiology · 2026Article
- The glutaminase (CgGLS-1) mediates anti-bacterial immunity by prompting cytokine synthesis and hemocyte apoptosis in Pacific oyster Crassostrea gigas.Scientific reports · 2021Article
- Characterization of Drosophila octopamine receptor neuronal expression using MiMIC-converted Gal4 lines.The Journal of comparative neurology · 2020Article
- Identification of the neurotransmitter profile of AmFoxP expressing neurons in the honeybee brain using double-label in situ hybridization.BMC neuroscience · 2018Article
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- Dendritic filopodia, Ripped Pocket, NOMPC, and NMDARs contribute to the sense of touch in Drosophila larvae.Current biology : CB · 2012Article
- Synchronized bilateral synaptic inputs to Drosophila melanogaster neuropeptidergic rest/arousal neurons.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2011Article
- Drosophila glial glutamate transporter Eaat1 is regulated by fringe-mediated notch signaling and is essential for larval locomotion.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2010Article
- Acute disruption of the NMDA receptor subunit NR1 in the honeybee brain selectively impairs memory formation.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2010Article
- Use of non-mammalian alternative models for neurotoxicological study.Neurotoxicology · 2008Review
- Eph receptor and ephrin signaling in developing and adult brain of the honeybee (Apis mellifera).Developmental neurobiology · 2007Article
- Reconstitution of invertebrate glutamate receptor function depends on stargazin-like proteins.Proceedings of the National Academy of Sciences of the United States of America · 2006Article
- Differential localization of glutamate receptor subunits at the Drosophila neuromuscular junction.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2004Article
- Fast synaptic currents in Drosophila mushroom body Kenyon cells are mediated by alpha-bungarotoxin-sensitive nicotinic acetylcholine receptors and picrotoxin-sensitive GABA receptors.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2003Article
- Insect NMDA receptors mediate juvenile hormone biosynthesis.Proceedings of the National Academy of Sciences of the United States of America · 2002Article
- Insertional mutation of the Drosophila nuclear lamin Dm0 gene results in defective nuclear envelopes, clustering of nuclear pore complexes, and accumulation of annulate lamellae.The Journal of cell biology · 1997Article
- Cloning and functional expression of a Drosophila metabotropic glutamate receptor expressed in the embryonic CNS.The Journal of neuroscience : the official journal of the Society for Neuroscience · 1996Article
- Structure and pharmacological properties of a molluscan glutamate-gated cation channel and its likely role in feeding behavior.The Journal of neuroscience : the official journal of the Society for Neuroscience · 1996Article
- Identification of an extracellular motif involved in the binding of guanine nucleotides by a glutamate receptor.The EMBO journal · 1996Article
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We report the isolation and functional characterization of cDNAs encoding a Drosophila kainate-selective glutamate receptor. The deduced mature 964-residue protein (DGluR-I) is 108,482 Da and exhibits significant homology to mammalian glutamate receptor subunits. Injection of DGluR-I cRNA into Xenopus oocytes generated kainate-operated ion channels which were blocked by the selective non-N-methyl-D-aspartate receptor antagonist 6-cyano-7-nitro-quinoxaline-2,3-dione and philanthotoxin. DGluR-I transcripts are differentially expressed during Drosophila development and, in late embryogenesis, accumulate in the central nervous system.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.