Evidence map›Paper›PMID 1351875›Full record

ArticleImmunogenetics1992

PFGE mapping and RFLP analysis of the S/D region of the mouse H-2 complex.

W P Lafuse, D Lanning, T Spies, C S David

Abstract read
PubMed Publisher
In one paragraph

Article in Immunogenetics, 1992. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 24 citations in OpenAlex.

  1. Characterization of recombination in the HLA class II region.American journal of human genetics · 1997
    Article
  2. A physical map of the mouse H2 Bat5/Db interval.Mammalian genome : official journal of the International Mammalian Genome Society · 1997
    Article
  3. Article
  4. Mapping of the SLA complex class III region by pulsed field gel electrophoresis.Mammalian genome : official journal of the International Mammalian Genome Society · 1995
    Article
  5. Article
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  7. Article
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  9. New microsatellite size variants as markers for a cross-over hotspot in the C4-H-2D region.Mammalian genome : official journal of the International Mammalian Genome Society · 1994
    Article
  10. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

W P LafuseDepartment of Medical Microbiology and Immunology, Ohio State University, Columbus 43210.
D Lanning
T Spies
C S David
The Ohio State University · USDana-Farber Cancer Institute · USMayo Clinic in Arizona · US

Funding

NIGMS NIH HHS GM41786
6 · The paper itself

Abstract

We have constructed a long range restriction map of the S/D segment of the mouse H-2 complex by pulsed field gel electrophoresis and hybridization with mouse cDNA probes to Bf and Tnfa genes and human cDNA probes to BAT2, BAT3, BAT4, BAT5, and BAT6 genes which have recently been mapped to the human HLA complex between C2 and HLA-B. The distance between the mouse C2 and Tnfa genes was found to be approximately 350 kilobases. The position of the mouse Bat genes in this map were found to be comparable to the position of the BAT genes in the human HLA complex. A panel of recombinant mouse strains was also examined by restriction fragment analysis with probes detecting the Hsp70, Bat5, and Tnfa genes. The results indicate that recombination in this segment is not random. No recombinants were found with crossovers between the C2 and Hsp70 genes and only one recombinant was found with a crossover between Tnfa and H-2D. In contrast, the crossover sites of 16 recombinants were mapped between the Hsp70 and Tnfa genes. Seven of these recombinants were found to have crossovers between Hsp70 and Bat5 and three recombinants were found to have crossover sites between Bat5 and Tnfa.

Indexed as

Major Histocompatibility ComplexAnimalsComplement C4GenesHeat-Shock ProteinsMicePolymorphism, Restriction Fragment LengthRestriction MappingTumor Necrosis Factor-alphaComplement C4Heat-Shock ProteinsTumor Necrosis Factor-alpha

Identifiers

PMID1351875
OpenAlexW2068147360

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.