Evidence map›Paper›PMID 1350556›Full record

ArticleGenetics1992

New molecular markers for the distal end of the t-complex and their relationships to mutations affecting mouse development.

T Ebersole, F Lai, K Artzt

Abstract read
In one paragraph

Article in Genetics, 1992. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Recombination within mouse t haplotypes has replaced significant segments of t-specific DNA.Mammalian genome : official journal of the International Mammalian Genome Society · 2008
    Article
  2. The cld mutation: narrowing the critical chromosomal region and selecting candidate genes.Mammalian genome : official journal of the International Mammalian Genome Society · 2006
    Article
  3. Isolation of candidate hybrid sterility 1 genes by cDNA selection in a 1.1 megabase pair region on mouse chromosome 17.Mammalian genome : official journal of the International Mammalian Genome Society · 1997
    Article
  4. Sub-milliMorgan map of the proximal part of mouse Chromosome 17 including the hybrid sterility 1 gene.Mammalian genome : official journal of the International Mammalian Genome Society · 1996
    Article
  5. Mouse H2 congenic intervals: analysis and use for mapping.Mammalian genome : official journal of the International Mammalian Genome Society · 1995
    Article
  6. Mapping around the Fused locus on mouse chromosome 17.Mammalian genome : official journal of the International Mammalian Genome Society · 1995
    Article
  7. Article
  8. Article
  9. Article
  10. Map positions of four dinucleotide repeats in the mouse t complex.Mammalian genome : official journal of the International Mammalian Genome Society · 1992
    Article
  11. Mouse chromosome 17.Mammalian genome : official journal of the International Mammalian Genome Society · 1992
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

T EbersoleDepartment of Zoology, University of Texas, Austin 78712-1064.
F Lai
K Artzt

Funding

Mammalian genetic analysis of embryonic neural overgrow*R01HD010668 · NICHD · UNIVERSITY OF TEXAS AUSTIN · PI ARTZT, KAREN J · 1985 to 2006
$2.5M
TERATOCARCINOMA AND EMBRYONAL TUMORS: SURFACE ANTIGENSR01CA021651 · NCI · UNIVERSITY OF TEXAS AUSTIN · PI ARTZT, KAREN J · 1985 to 1992
–
NCI NIH HHS CA21651NICHD NIH HHS HD10668
6 · The paper itself

Abstract

Many mutations affecting mouse development have been mapped to the t-complex of mouse chromosome 17. We have obtained 17 cosmid clones as molecular markers for this region by screening a hamster-mouse chromosome 17 and 18 cell hybrid cosmid library with mouse-specific repetitive elements and mapping positive clones via t-haplotype vs. C3H restriction fragment length polymorphism (RFLP) analysis. Twelve of the clones mapping distal to Leh66B in t-haplotypes are described here. Using standard RFLP analysis or simple sequence length polymorphism between t-haplotypes, exceptional partial t-haplotypes and nested sets of inter-t-haplotype recombinants, five cosmids have been mapped in or around In(17)3 and seven in the most distal inversion In17(4). More precise mapping of four of the cosmids from In(17)4 shows that they will be useful in the molecular identification of some of the recessive lethals mapped to the t-complex: two cosmids map between H-2K and Crya-1, setting a distal limit in t-haplotypes for the position of the tw5 lethal, one is inseparable from the tw12 lethal, and one maps distal to tf near the t0(t6) lethal and cld.

Indexed as

Genetic MarkersMutationAnimalsBase SequenceChromosome MappingCosmidsElectrophoresis, Agar GelGenes, LethalGenes, RecessiveHaplotypesMiceMice, Inbred C3HMolecular Sequence DataNucleic Acid HybridizationPolymorphism, Restriction Fragment LengthRecombination, GeneticGenetic Markers

Identifiers

PMID1350556
PMCPMC1204951

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.