Evidence map›Paper›PMID 1348494›Full record

ArticleImmunogenetics1992

Mapping of the genes encoding tum- transplantation antigens P91A, P35B, and P198.

P J Dyson, C de Smet, A M Knight, D Simon-Chazottes, J L Guénet, T Boon

Abstract read
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In one paragraph

Article in Immunogenetics, 1992. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 3 countries.

P J DysonClinical Research Centre, Harrow, Middlesex, UK.
C de Smet
A M Knight
D Simon-Chazottes
J L Guénet
T Boon
Institut Pasteur · FRLudwig Cancer Research · BEMiddlesex University · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tum- comprises a class of genes, mutation of which in P815 tumor cells has led to the acquisition of new cytotoxic T cell-recognized epitopes. The cells carrying the mutant alleles have impaired tumorigenicity compared with their progenitors due to in vivo induction of a cytotoxic T-cell response specific for tum- antigens. Two tum- genes, P91A and P35B, were found to be single copy loci mapping to chromosomes 11 and 15 respectively. A third, P198, was found to map to chromosome 7 and to be a member of a small gene family with other members on chromosomes 13, 14, and 15. Multiple P198-related sequences were found in other mammalian species suggesting the P198 related gene family is a general feature of mammalian genomes.

Indexed as

Chromosome MappingAnimalsAntigens, NeoplasmBase SequenceBlotting, SouthernCricetinaeGenetic LinkageHistocompatibility AntigensMiceMice, Inbred StrainsMolecular Sequence DataPolymerase Chain ReactionPolymorphism, GeneticPolymorphism, Restriction Fragment LengthAntigens, NeoplasmHistocompatibility Antigenstumor-associated transplantation antigen

Identifiers

PMID1348494
OpenAlexW2083199864

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.