ArticleImmunogenetics1992
Tumor induction by the LTR, v-src, LTR DNA in four B (MHC) congenic lines of chickens.
Article in Immunogenetics, 1992. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
10 citing papers in PubMed, 32 citations in OpenAlex.
- The full recovery of mice (Mus Musculus C57BL/6 strain) from virus-induced sarcoma after treatment with a complex of DDMC delivery system and sncRNAs.Non-coding RNA research · 2019Article
- On board a raft or boat in the retrovirus sea.Proceedings of the National Academy of Sciences of the United States of America · 2016Article
- Brief review of the chicken Major Histocompatibility Complex: the genes, their distribution on chromosome 16, and their contributions to disease resistance.Poultry science · 2016Review
- Intronic deletions that disrupt mRNA splicing of the tva receptor gene result in decreased susceptibility to infection by avian sarcoma and leukosis virus subgroup A.Journal of virology · 2012Article
- The transcription factor EGR1 regulates metastatic potential of v-src transformed sarcoma cells.Cellular and molecular life sciences : CMLS · 2010Article
- Proviruses selected for high and stable expression of transduced genes accumulate in broadly transcribed genome areas.Journal of virology · 2010Article
- CpG island protects Rous sarcoma virus-derived vectors integrated into nonpermissive cells from DNA methylation and transcriptional suppression.Proceedings of the National Academy of Sciences of the United States of America · 2001Article
- Endogenous c-src as a determinant of the tumorigenicity of src oncogenes.Proceedings of the National Academy of Sciences of the United States of America · 1996Article
- src-specific immunity in inbred chickens bearing v-src DNA- and RSV-induced tumors.Immunogenetics · 1994Article
- Deletions in the DNA-binding domain of the TP53 gene in v-src-transformed chicken cells.In vitro cellular & developmental biology. AnimalArticle
Corrections and comments
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Authors and funding
6 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We report that the cloned DNA harboring the long terminal repeat (LTR), v-src, LTR proviral structure is tumorigenic in chickens of the Prague congenic lines. The growth rate of these tumors is by far the highest in the recombinant CC.R1 line, the B haplotype of which is composed of the B-F/L4 and B-G12 subregions originating from different naturally occurring haplotypes. Some of the tumors induced by the LTR, v-src, LTR DNA are repeatedly transplantable in syngeneic chickens, maintain unaltered provirus, and express v-src mRNA. Differences in the response to challenge with Rous sarcoma virus (RSV) and LTR, v-src, LTR DNA on a given experimental model are compared and possible involvement of an interaction between B-F/L and B-G region genes is considered. Regression of the LTR, v-src, LTR DNA-induced tumors did not prevent the formation and growth of tumors induced subsequently by RSV.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.