ArticleProceedings of the National Academy of Sciences of the United States of America1992
The major histocompatibility complex class I antigen-binding protein p88 is the product of the calnexin gene.
Article in Proceedings of the National Academy of Sciences of the United States of America, 1992. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
22 citing papers in PubMed, 74 citations in OpenAlex.
- Two endoplasmic reticulum proteins (calnexin and calreticulin) are involved in innate immunity in Chinese mitten crab (Eriocheir sinensis).Scientific reports · 2016Article
- Dopaminergic modulation of the hippocampal neuropil proteome identified by bioorthogonal noncanonical amino acid tagging (BONCAT).Proteomics · 2012Article
- Structure and intracellular targeting of the SARS-coronavirus Orf7a accessory protein.Structure (London, England : 1993) · 2005Article
- Molecular biology of nickel carcinogenesis: identification of differentially expressed genes in morphologically transformed C3H10T1/2 Cl 8 mouse embryo fibroblast cell lines induced by specific insoluble nickel compounds.Molecular and cellular biochemistry · 2004Article
- Molecular biology of deregulated gene expression in transformed C3H/10T1/2 mouse embryo cell lines induced by specific insoluble carcinogenic nickel compounds.Environmental health perspectives · 2002Article
- Changes in the levels of seven proteins involved in polypeptide folding and transport during endosperm development of two barley genotypes differing in storage protein localisation.Plant molecular biology · 1998Article
- Intermediates in the assembly and degradation of class I major histocompatibility complex (MHC) molecules probed with free heavy chain-specific monoclonal antibodies.The Journal of experimental medicine · 1996Article
- Deglucosylation of N-linked glycans is an important step in the dissociation of calreticulin-class I-TAP complexes.Proceedings of the National Academy of Sciences of the United States of America · 1996Article
- Calnexin acts as a molecular chaperone during the folding of glycoprotein B of human cytomegalovirus.Journal of virology · 1996Article
- A novel interleukin-12 p40-related protein induced by latent Epstein-Barr virus infection in B lymphocytes.Journal of virology · 1996Article
- Species-specific differences in chaperone interaction of human and mouse major histocompatibility complex class I molecules.The Journal of experimental medicine · 1995Article
- Maturation of the trans-Golgi network protease furin: compartmentalization of propeptide removal, substrate cleavage, and COOH-terminal truncation.The Journal of cell biology · 1994Article
- An unstable beta 2-microglobulin: major histocompatibility complex class I heavy chain intermediate dissociates from calnexin and then is stabilized by binding peptide.The Journal of experimental medicine · 1994Article
- Calreticulin: not just another calcium-binding protein.Molecular and cellular biochemistry · 1994Review
- Human cytomegalovirus-infected cells have unstable assembly of major histocompatibility complex class I complexes and are resistant to lysis by cytotoxic T lymphocytes.Journal of virology · 1994Article
- How N-linked oligosaccharides affect glycoprotein folding in the endoplasmic reticulum.Molecular biology of the cell · 1994Review
- A selective defect in IgM antigen receptor synthesis and transport causes loss of cell surface IgM expression on tolerant B lymphocytes.The EMBO journal · 1994Article
- A role for calnexin (IP90) in the assembly of class II MHC molecules.The EMBO journal · 1994Article
- Role of N-linked oligosaccharide recognition, glucose trimming, and calnexin in glycoprotein folding and quality control.Proceedings of the National Academy of Sciences of the United States of America · 1994Article
- Folding and assembly of major histocompatibility complex class I heterodimers in the endoplasmic reticulum of intact cells precedes the binding of peptide.The Journal of experimental medicine · 1993Article
Corrections and comments
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Authors and funding
10 authors at 1 institution in 1 country.
Funding
Abstract
A 90-kDa phosphoprotein (p90) of the endoplasmic reticulum was identified by a monoclonal antibody generated against human hepatoma cells. Pulse-chase experiments with [32P]phosphate and [35S]methionine demonstrated that p90 formed both stable and transient complexes with other cellular proteins, suggesting its role as a molecular chaperone. This protein associates with heavy chains of major histocompatibility complex class I proteins, suggesting that it is the human homolog of the recently described 88-kDa protein that transiently associates with murine class I molecules in the endoplasmic reticulum. The p90 protein also associates in B lymphocytes with membrane immunoglobulin mu heavy chains and may serve as a chaperone for many membrane-bound polypeptides. A partial human p90 cDNA was cloned from a lambda gt11 expression library and identified as the human homolog of calnexin, a major canine calcium-binding protein found to be associated with the signal-sequence receptor in endoplasmic reticulum membranes.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.