ArticlePflugers Archiv : European journal of physiology1992
Modulation of fatty-acid-binding protein content of rat heart and skeletal muscle by endurance training and testosterone treatment.
Article in Pflugers Archiv : European journal of physiology, 1992. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed, 85 citations in OpenAlex.
- Testosterone therapy induces molecular programming augmenting physiological adaptations to resistance exercise in older men.Journal of cachexia, sarcopenia and muscle · 2019Trial
- Article
- Androgen interacts with exercise through the mTOR pathway to induce skeletal muscle hypertrophy.Biology of sport · 2017Article
- Migration-induced variation of fatty acid transporters and cellular metabolic intensity in passerine birds.Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology · 2015Article
- Testosterone and insulin resistance in the metabolic syndrome and T2DM in men.Nature reviews. Endocrinology · 2013Article
- Antagonism of P2Y1-induced vasorelaxation by acyl CoA: a critical role for palmitate and 3'-phosphate.British journal of pharmacology · 2013Article
- Molecular cloning and functional analysis of the fatty acid-binding protein (Sp-FABP) gene in the mud crab (Scylla paramamosain).Genetics and molecular biology · 2013Article
- Molecular cloning and tissue expression of the fatty acid-binding protein (Es-FABP9) gene in the reproduction seasons of Chinese mitten crab, Eriocheir sinensis.Molecular biology reports · 2011Article
- Molecular cloning and tissue expression of the fatty acid-binding protein (Es-FABP) gene in female Chinese mitten crab (Eriocheir sinensis).BMC molecular biology · 2010Article
- The transcriptional corepressor RIP140 regulates oxidative metabolism in skeletal muscle.Cell metabolism · 2007Article
- Fatty acid-dependent expression of the muscle FABP gene - comparative analysis of gene control in functionally related, but evolutionary distant animal systems.Molecular and cellular biochemistry · 2007Article
- Energy substrate metabolism in cardiac hypertrophy.Current hypertension reports · 2004Review
- Effect of testosterone and endurance training on glycogen metabolism in skeletal muscle of chronic hyperglycaemic female rats.British journal of sports medicine · 2003Article
- Characterization of a new fatty acid response element that controls the expression of the locust muscle FABP gene.Molecular and cellular biochemistry · 2002Article
- Down-regulation of heart HFABP and UCP2 gene expression in diet-induced (cafeteria) obese rats.Journal of physiology and biochemistry · 2002Article
- Induction of cardiac FABP gene expression by long chain fatty acids in cultured rat muscle cells.Molecular and cellular biochemistry · 2001Article
- Fatty acid-binding proteins in the heart.Molecular and cellular biochemistry · 1998Review
- Characterization of free and glyceride-esterified long chain fatty acids in different skeletal muscle types of the rat.Molecular and cellular biochemistry · 1998Article
- Transcriptional regulation of muscle fatty acid-binding protein.The Biochemical journal · 1994Article
- Modulation of glycogen metabolism of rat skeletal muscles by endurance training and testosterone treatment.Pflugers Archiv : European journal of physiology · 1993Article
Corrections and comments
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The effects of training and/or testosterone treatment and its aromatization to oestradiol on fatty-acid-binding protein (FABP) content and cytochrome c oxidase activity in heart, soleus and extensor digitorum longus (EDL) muscles were studied in intact adult female rats. One group of rats remained sedentary, whereas the others were trained for 7 weeks. Thereafter the trained rats were divided into control and testosterone-treated groups, with or without an aromatase inhibitor. Testosterone was administered by a silastic implant. Training was continued for 2 weeks. In untreated sedentary rats the immunochemically assayed FABP contents were 497 +/- 28, 255 +/- 49 and 58 +/- 17 micrograms/g wet weight for the heart, soleus, and EDL respectively. In the heart the FABP content was increased after training (29%), testosterone treatment (33%) or both manipulations (53%). In soleus muscle FABP increased only after testosterone treatment (16%), whereas in EDL no changes were found. Inhibiting the aromatase enzyme complex abolished the testosterone-induced effect on FABP content in soleus (suggesting an oestradiol effect) but not in heart muscle. Among the three muscles studied the FABP content was found to be related to the cytochrome c oxidase activity in a non-linear way. In conclusion, it is shown that the FABP contents and mitochondrial activities of heart and skeletal muscle are affected by training and sex hormones and that these effects are different for heart and skeletal muscles.
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