Evidence map›Paper›PMID 1326672›Full record

ArticleJournal of virology1992

Loss of transformed phenotype upon senescence of Rous sarcoma virus-infected chicken neuroretinal cells.

G M Seigel, M F Notter

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of virology, 1992. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Establishment of an E1A-immortalized retinal cell culture.In vitro cellular & developmental biology. Animal · 1996
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

G M SeigelDepartment of Neurobiology and Anatomy, University of Rochester Medical Center, New York 14642.
M F Notter

Funding

RETINAL GROWTH AND DIFFERENTIATION--EFFECT OF ONCOGENESR01EY006947 · NEI · UNIVERSITY OF ROCHESTER · PI DEL CERRO, MANUEL · 1988 to 1990
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TRAINING IN GERIATRICS AND NEUROBIOLOGY OF AGINGT32AG000107 · NIA · UNIVERSITY OF ROCHESTER · PI COLEMAN, PAUL D · 1985 to 1999
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NEI NIH HHS EY06947NIA NIH HHS T32AG00107
6 · The paper itself

Abstract

Success in obtaining permanent Rous sarcoma virus-infected chicken cell lines has been limited because of a senescence phenomenon. We show that a diminished, transformed phenotype, followed by dramatic morphological changes, precedes senescence. These changes are associated with continued expression of pp60v-src, as well as specific alterations in expression of two possible phosphorylated substrates of pp60v-src.

Indexed as

Cell Transformation, ViralAnimalsAvian Sarcoma VirusesBlotting, WesternCell AdhesionCells, CulturedCellular SenescenceChick EmbryoMitosisPhenotypePhosphoproteinsRetinaPhosphoproteins

Identifiers

PMID1326672
PMCPMC283681

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.