ReviewJournal of bioenergetics and biomembranes1992
The ligand-binding domain of rhodopsin and other G protein-linked receptors.
Review in Journal of bioenergetics and biomembranes, 1992. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed, 109 citations in OpenAlex.
- Local peptide movement in the photoreaction intermediate of rhodopsin.Proceedings of the National Academy of Sciences of the United States of America · 2006Article
- A proposed structure for transmembrane segment 7 of G protein-coupled receptors incorporating an asn-Pro/Asp-Pro motif.Biophysical journal · 1998Article
- BUNDLE: a program for building the transmembrane domains of G-protein-coupled receptors.Journal of computer-aided molecular design · 1998Article
- The C9 methyl group of retinal interacts with glycine-121 in rhodopsin.Proceedings of the National Academy of Sciences of the United States of America · 1997Article
- The transmembrane 7-alpha-bundle of rhodopsin: distance geometry calculations with hydrogen bonding constraints.Biophysical journal · 1997Article
- Projection structure of frog rhodopsin in two crystal forms.Proceedings of the National Academy of Sciences of the United States of America · 1995Article
- Automated method for modeling seven-helix transmembrane receptors from experimental data.Biophysical journal · 1995Article
- Removal of transducer HtrI allows electrogenic proton translocation by sensory rhodopsin I.Proceedings of the National Academy of Sciences of the United States of America · 1994Article
- Opsins with mutations at the site of chromophore attachment constitutively activate transducin but are not phosphorylated by rhodopsin kinase.Proceedings of the National Academy of Sciences of the United States of America · 1994Article
- Photoactivation of rhodopsin involves alterations in cysteine side chains: detection of an S-H band in the Meta I-->Meta II FTIR difference spectrum.Biophysical journal · 1994Article
- Color sensing in the Archaea: a eukaryotic-like receptor coupled to a prokaryotic transducer.Journal of bacteriology · 1993Review
- The probable arrangement of the helices in G protein-coupled receptors.The EMBO journal · 1993Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
Abstract
Rhodopsin is a member of the very large family of G protein-linked receptors. The members of this family show clear signs of evolutionary relatedness, primarily in amino acid sequence homology, topographical structure of the proteins in the membrane, and the fact that all of the receptors function through the intermediary action of a GTP-binding regulatory protein or G protein. Recently, it has become clear that the structural similarity of these receptors extends well beyond the rather crude comparison of membrane topography. Reviewed here are several studies in which site-directed mutagenesis and active-site-directed reagents were used to show that the ligand-binding pockets of these receptors are highly similar. They are similar despite the fact that the structures of their various ligands are very different.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.