ArticleJournal of virology1992
The surface envelope protein gene region of equine infectious anemia virus is not an important determinant of tropism in vitro.
Article in Journal of virology, 1992. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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Who cites it
24 citing papers in PubMed, 59 citations in OpenAlex.
- Twin gradients in APOBEC3 edited HIV-1 DNA reflect the dynamics of lentiviral replication.Nucleic acids research · 2006Article
- A tumor necrosis factor receptor family protein serves as a cellular receptor for the macrophage-tropic equine lentivirus.Proceedings of the National Academy of Sciences of the United States of America · 2005Article
- Equine infectious anemia virus Gag p9 function in early steps of virus infection and provirus production.Journal of virology · 2005Article
- Evolution of the equine infectious anemia virus long terminal repeat during the alteration of cell tropism.Journal of virology · 2005Article
- APOBEC3G is a single-stranded DNA cytidine deaminase and functions independently of HIV reverse transcriptase.Nucleic acids research · 2004Article
- Characterization of a cytolytic strain of equine infectious anemia virus.Journal of virology · 2003Article
- Article
- Gag protein epitopes recognized by ELA-A-restricted cytotoxic T lymphocytes from horses with long-term equine infectious anemia virus infection.Journal of virology · 1998Article
- Equine endothelial cells support productive infection of equine infectious anemia virus.Journal of virology · 1998Article
- Equine infectious anemia virus is found in tissue macrophages during subclinical infection.Journal of virology · 1998Article
- Development and characterization of an in vivo pathogenic molecular clone of equine infectious anemia virus.Journal of virology · 1998Article
- Disease induction by virus derived from molecular clones of equine infectious anemia virus.Journal of virology · 1998Article
- Localized sequence heterogeneity in the long terminal repeats of in vivo isolates of equine infectious anemia virus.Journal of virology · 1997Article
- Genetic drift can dominate short-term human immunodeficiency virus type 1 nef quasispecies evolution in vivo.Journal of virology · 1997Article
- Genomic quasispecies associated with the initiation of infection and disease in ponies experimentally infected with equine infectious anemia virus.Journal of virology · 1996Article
- Fate of direct and inverted repeats in the RNA hypermutagenesis reaction.Nucleic acids research · 1996Article
- Equine infectious anemia virus replication is upregulated during differentiation of blood monocytes from acutely infected horses.Journal of virology · 1996Article
- Genetic analysis of the major homology region of the Rous sarcoma virus Gag protein.Journal of virology · 1995Article
- Enhanced sensitivity to neutralizing antibodies in a variant of equine infectious anemia virus is linked to amino acid substitutions in the surface unit envelope glycoprotein.Journal of virology · 1995Article
- Hypermutagenesis of RNA using human immunodeficiency virus type 1 reverse transcriptase and biased dNTP concentrations.Proceedings of the National Academy of Sciences of the United States of America · 1994Article
Corrections and comments
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Authors and funding
9 authors at 1 institution in 1 country.
Funding
Abstract
Virulent, wild-type equine infectious anemia virus (EIAV) is restricted in one or more early steps in replication in equine skin fibroblast cells compared with cell culture-adapted virus, which is fully competent for replication in this cell type. We compared the sequences of wild-type EIAV and a full-length infectious proviral clone of the cell culture-adapted EIAV and found that the genomes were relatively well conserved with the exception of the envelope gene region, which showed extensive sequence differences. We therefore constructed several wild-type and cell culture-adapted virus chimeras to examine the role of the envelope gene in replication in different cell types in vitro. Unlike wild-type virus, which is restricted by an early event(s) for replication in equine dermis cells, the wild-type outer envelope gene chimeras are replication competent in this cell type. We conclude that even though there are extensive sequence differences between wild-type and cell culture-adapted viruses in the surface envelope gene region, this domain is not a determinant of the differing in vitro cell tropisms.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.