ArticleJournal of virology2003
Genome of bovine herpesvirus 5.
Article in Journal of virology, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
42 citing papers in PubMed, 175 citations in OpenAlex.
- Review
- Herpesviruses: overview of systematics, genomic complexity and life cycle.Virology journal · 2025Review
- Genome sequence of bovine herpesvirus 5 (BoHV-5) isolate from India.Microbiology resource announcements · 2025Article
- Functions of the UL51 protein during the herpesvirus life cycle.Frontiers in microbiology · 2024Review
- Bovine herpesvirus meningoencephalitis in the State of Tocantins, Brazil.Brazilian journal of veterinary medicine · 2024Article
- Neutralizing antibodies to bovine and bubaline alphaherpesviruses in water buffaloes (Bubalus bubalis).Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2023Article
- Complete Genome Sequences of Two Bovine Alphaherpesvirus 5 Subtype C Strains from Southeast Brazil.Microbiology resource announcements · 2022Article
- Brain-derived neurotrophic factor is down regulated after bovine alpha-herpesvirus 5 infection in both wild-type and TLR3/7/9 deficient mice.The Journal of veterinary medical science · 2021Article
- Functional analysis of the latency-related gene of bovine herpesvirus types 1 and 5.Journal of neurovirology · 2019Article
- Latent bovine herpesvirus 1 and 5 in milk from naturally infected dairy cattle.The Journal of veterinary medical science · 2018Article
- Cloning and sequencingVeterinary world · 2018Article
- Article
- Article
- Bovine herpesviruses induce different cell death forms in neuronal and glial-derived tumor cell cultures.Journal of neurovirology · 2016Article
- Article
- Genome Sequence of Canine Herpesvirus.PloS one · 2016Article
- Epidemiology and genetic characterization of BVDV, BHV-1, BHV-4, BHV-5 and Brucella spp. infections in cattle in Turkey.The Journal of veterinary medical science · 2015Article
- Sequence analysis of the 5' third of glycoprotein C gene of South American bovine herpesviruses 1 and 5.Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologica · 2015Article
- Bovine herpesvirus glycoprotein D: a review of its structural characteristics and applications in vaccinology.Veterinary research · 2014Review
- Genetic diversity of 3' region of glycoprotein D gene of bovine herpesvirus 1 and 5.Virus genes · 2014Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 4 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Here we present the complete genomic sequence of bovine herpesvirus 5 (BHV-5), an alphaherpesvirus responsible for fatal meningoencephalitis in cattle. The 138390-bp genome encodes 70 putative proteins and resembles the alpha2 subgroup of herpesviruses in genomic organization and gene content. BHV-5 is very similar to BHV-1, the etiological agent of infectious bovine rhinotracheitis, as reflected by the high level of amino acid identity in their protein repertoires (average, 82%). The highest similarity to BHV-1 products (>or=95% amino acid identity) is found in proteins involved in viral DNA replication and processing (UL5, UL15, UL29, and UL39) and in virion proteins (UL14, UL19, UL48, and US6). Among the least conserved (<or=75%) are the homologues of immediate-early (IE) proteins BICP0, BICP4, and BICP22, the three proteins being longer in BHV-5 than in BHV-1. The structure of the BHV-5 latency-related (LR) region departs markedly from that of BHV-1 in both coding and transcriptional regulatory regions. Given the potential significance of IE genes and the LR region in virus-neuron interactions, it is likely these differences contribute to BHV-5 neuropathogenicity.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.