Trial reportJAMA2003
Effect of exercise duration and intensity on weight loss in overweight, sedentary women: a randomized trial.
Trial report in JAMA, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00006315 (Dose/Response of Exercise on Long Term Weight Loss), which is not on this map. Cited by 151 papers, 13 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Dose/Response of Exercise on Long Term Weight Loss
Who cites it
151 citing papers in PubMed, 13 syntheses or guidelines pooled it, 518 citations in OpenAlex.
- Comparing exercise modalities during caloric restriction: a systematic review and network meta-analysis on body composition.Frontiers in nutrition · 2025Pooled it
- The Effect of Low-Volume High-Intensity Interval Training on Body Composition and Cardiorespiratory Fitness: A Systematic Review and Meta-Analysis.Sports medicine (Auckland, N.Z.) · 2019Pooled it
- The Impact of Long-Term Physical Activity Interventions for Overweight/Obese Postmenopausal Women on Adiposity Indicators, Physical Capacity, and Mental Health Outcomes: A Systematic Review.Journal of obesity · 2016Pooled it
- Predictors of Energy Compensation during Exercise Interventions: A Systematic Review.Nutrients · 2015Pooled it
- 2013 AHA/ACC/TOS guideline for the management of overweight and obesity in adults: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines and The Obesity Society.Circulation · 2014 · on this mapGuideline
- What are the most effective techniques in changing obese individuals' physical activity self-efficacy and behaviour: a systematic review and meta-analysis.The international journal of behavioral nutrition and physical activity · 2013Pooled it
- Exercise and type 2 diabetes: the American College of Sports Medicine and the American Diabetes Association: joint position statement.Diabetes care · 2010Guideline
- Effect of school-based physical activity interventions on body mass index in children: a meta-analysis.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2009Pooled it
- Characteristics of physical activity guidelines and their effect on adherence: a review of randomized trials.Sports medicine (Auckland, N.Z.) · 2009Pooled it
- Management of obesity in adults: European clinical practice guidelines.Obesity facts · 2008Guideline
- 2006 Canadian clinical practice guidelines on the management and prevention of obesity in adults and children [summary].CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2007Guideline
- Exercise for overweight or obesity.The Cochrane database of systematic reviews · 2006 · on this mapPooled it
- Effectiveness of weight loss and maintenance interventions in women.Current diabetes reports · 2004Pooled it
- Effect of weight loss through dietary interventions on cardiometabolic health in older adults.International journal of obesity (2005) · 2025Trial
- Effect of physical activity on changes in weight and aerobic capacity during an 18-month behavioral weight loss intervention.The international journal of behavioral nutrition and physical activity · 2025Trial
- Effects of Weight Loss and Weight Maintenance on Lipoprotein Insulin Resistance Scores in Adults with Overweight and Obesity.Metabolic syndrome and related disorders · 2024Trial
- Physical activity and weight loss in a pragmatic weight loss trial.International journal of obesity (2005) · 2023Trial
- Impact of weight loss with diet or diet plus physical activity on cardiac magnetic resonance imaging and cardiovascular disease risk factors: Heart Health Study randomized trial.Obesity (Silver Spring, Md.) · 2022Trial
- Effect of exercise training after bariatric surgery: A 5-year follow-up study of a randomized controlled trial.PloS one · 2022Trial
- Unsupervised Exercise Training Was Not Found to Improve the Metabolic Health or Phenotype over a 6-Month Dietary Intervention: A Randomised Controlled Trial with an Embedded Economic Analysis.International journal of environmental research and public health · 2021Trial
91 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
Abstract
contextA higher duration and intensity of exercise may improve long-term weight loss.
objectiveTo compare the effects of different durations and intensities of exercise on 12-month weight loss and cardiorespiratory fitness. DESIGN, SETTING, AND
participantsRandomized trial conducted from January 2000 through December 2001 involving 201 sedentary women (mean [SD] age, 37.0 [5.7] years; mean [SD] body mass index, 32.6 [4.2]) in a university-based weight control program.
interventionParticipants were randomly assigned to 1 of 4 exercise groups (vigorous intensity/high duration; moderate intensity/high duration; moderate intensity/moderate duration; or vigorous intensity/moderate duration) based on estimated energy expenditure (1000 kcal/wk vs 2000 kcal/wk) and exercise intensity (moderate vs vigorous). All women were instructed to reduce intake of energy to between 1200 and 1500 kcal/d and dietary fat to between 20% and 30% of total energy intake.
main outcome measuresBody weight, cardiorespiratory fitness, and exercise participation.
resultsAfter exclusions, 184 of 196 randomized participants completed 12 months of treatment (94%). In intention-to-treat analysis, mean (SD) weight loss following 12 months of treatment was statistically significant (P <.001) in all exercise groups (vigorous intensity/high duration = 8.9 [7.3] kg; moderate intensity/high duration = 8.2 [7.6] kg; moderate intensity/moderate duration = 6.3 [5.6] kg; vigorous intensity/moderate duration = 7.0 [6.4] kg), with no significant difference between groups. Mean (SD) cardiorespiratory fitness levels also increased significantly (P =.04) in all groups (vigorous intensity/high duration = 22.0% [19.9%]; moderate intensity/high duration = 14.9% [18.6%]; moderate intensity/moderate duration = 13.5% [16.9%]; vigorous intensity/moderate duration = 18.9% [16.9%]), with no difference between groups. Post hoc analysis revealed that percentage weight loss at 12 months was associated with the level of physical activity performed at 6 and 12 months. Women reporting less than 150 min/wk had a mean (SD) weight loss of 4.7% [6.0%]; inconsistent (other) pattern of physical activity, 7.0% [6.9%]; 150 min/wk or more, 9.5% [7.9%]; and 200 min/wk or more of exercise, 13.6% [7.8%].
conclusionsSignificant weight loss and improved cardiorespiratory fitness were achieved through the combination of exercise and diet during 12 months, although no differences were found based on different exercise durations and intensities in this group of sedentary, overweight women.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.