Evidence map›Paper›PMID 12965936›Full record

ArticleClinical and diagnostic laboratory immunology2003

Serotyping isolates of Anaplasma phagocytophilum by using monoclonal antibodies.

Hisashi Inokuma, Philippe Brouqui, J Stephen Dumler, Didier Raoult

Abstract readComparative Study
In one paragraph

Article in Clinical and diagnostic laboratory immunology, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Trial
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Hisashi InokumaLaboratory of Veterinary Internal Medicine, Faculty of Agriculture, Yamaguchi University, 753-8515 Yamaguchi, Japan.
Philippe Brouqui
J Stephen Dumler
Didier Raoult

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ten mouse monoclonal antibodies (MAbs) that react with Anaplasma phagocytophilum (the human granulocytic ehrlichiosis agent) Webster isolates were developed. Seven different isolates of A. phagocytophilum were subtyped with these MAbs. Western blot analysis revealed that these MAbs reacted mainly with 41- to 46-kDa Msp2 proteins. Six MAbs reacted with all isolates. Four other MAbs reacted with human isolates from Wisconsin, but not with human isolates from New York or with animal isolates. Three different serotypes were identified. These features may lead to the development of other specific MAbs in order to provide tools for antigenic characterization of human isolates of A. phagocytophilum.

Indexed as

Anaplasma phagocytophilumAnimalsAntibodies, BacterialAntibodies, MonoclonalAntigens, BacterialBacterial Outer Membrane ProteinsBlotting, WesternFemaleFluorescent Antibody TechniqueHL-60 CellsHumansMiceMice, Inbred BALB CSerotypingAntibodies, BacterialAntibodies, MonoclonalAntigens, BacterialBacterial Outer Membrane Proteinsp44 protein, Anaplasma phagocytophila

Identifiers

PMID12965936
PMCPMC193879

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.