ArticleClinical and diagnostic laboratory immunology2003
Development and evaluation of a Western blot kit for diagnosis of human trichinellosis.
Article in Clinical and diagnostic laboratory immunology, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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Who cites it
24 citing papers in PubMed, 91 citations in OpenAlex.
- Effective Laboratory Diagnosis of Parasitic Infections of the Gastrointestinal Tract: Where, When, How, and What Should We Look For?Diagnostics (Basel, Switzerland) · 2024Review
- Early diagnosis ofVeterinary world · 2024Article
- Letter to the editor regarding - pleural effusion caused by Trichinella spiralis infection: two case reports.BMC infectious diseases · 2024Article
- Development of a rapid and sensitive immunochromatographic strip based on EuNPs-ES fluorescent probe for the detection of early Trichinella spiralis-specific IgG antibody in pigs.Veterinary research · 2021Article
- A common source for a trichinellosis outbreak reported in France and Serbia in 2017.Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2020Article
- International Commission on Trichinellosis: Recommendations on the use of serological tests for the detection ofFood and waterborne parasitology · 2019Review
- Serological tools for detection ofOne health (Amsterdam, Netherlands) · 2016Review
- New diagnostic antigens for early trichinellosis: the excretory-secretory antigens of Trichinella spiralis intestinal infective larvae.Parasitology research · 2015Article
- Early serodiagnosis of trichinellosis by ELISA using excretory-secretory antigens of Trichinella spiralis adult worms.Parasites & vectors · 2015Article
- Identification of early diagnostic antigens from major excretory-secretory proteins of Trichinella spiralis muscle larvae using immunoproteomics.Parasites & vectors · 2014Article
- Mast cell chymase degrades the alarmins heat shock protein 70, biglycan, HMGB1, and interleukin-33 (IL-33) and limits danger-induced inflammation.The Journal of biological chemistry · 2014Article
- Immunogenicity of mycobacterial vesicles in humans: identification of a new tuberculosis antibody biomarker.Tuberculosis (Edinburgh, Scotland) · 2013Article
- Proteomic analysis of Trichinella spiralis muscle larval excretory-secretory proteins recognized by early infection sera.BioMed research international · 2013Article
- Outbreak of human trichinellosis in Northern California caused by Trichinella murrelli.The American journal of tropical medicine and hygiene · 2012Article
- Comparative analysis of excretory-secretory antigens of Trichinella spiralis and Trichinella britovi muscle larvae by two-dimensional difference gel electrophoresis and immunoblotting.Proteome science · 2012Article
- The protective effect of the recombinant 53-kDa protein of Trichinella spiralis on experimental colitis in mice.Digestive diseases and sciences · 2011Article
- Validation of a Western Blot for the detection of anti-Trichinella spp. antibodies in domestic pigs.Parasitology research · 2009Article
- Update on eosinophilic meningoencephalitis and its clinical relevance.Clinical microbiology reviews · 2009Review
- Validation of an enzyme-linked immunosorbent assay for diagnosis of human trichinellosis.Clinical and vaccine immunology : CVI · 2008Article
- Species-specific antibody responses to the recombinant 53-kilodalton excretory and secretory proteins in mice infected with Trichinella spp.Clinical and vaccine immunology : CVI · 2008Article
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We evaluated industrially prepared Western blot strips designed to avoid the cross-reactions observed with indirect immunofluorescence and enzyme-linked immunosorbent assays used for the serodiagnosis of trichinellosis. The antigen preparations were crude extracts of Trichinella spiralis. The Western blot profile characteristic of trichinellosis was characterized by comparing 60 sera from patients infected by Trichinella to 11 sera from healthy subjects, 51 sera from patients with other proven parasitic diseases (cysticercosis, schistosomiasis, strongyloidosis, fascioliasis, toxocariasis, liver amebiasis, anisakiasis, filariasis, toxoplasmosis, hydatidosis, or malaria), and 23 sera from patients with autoantibodies. Specific 43- to 44-kDa and 64-kDa bands were obtained with all of the sera from 51 patients with acute trichinellosis, in 4 out of 9 patients at the early stages of the disease, and in only 1 control patient, who had suspected anisakiasis and in whom trichinellosis could not be ruled out by muscle biopsy.
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