ReviewThe Journal of membrane biology2003
Phagosome maturation: a few bugs in the system.
Review in The Journal of membrane biology, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
44 citing papers in PubMed.
- The lipid A acylation pattern of Coxiella burnetii prevents detection and clearance by the non-canonical inflammasome in primary murine macrophages.PLoS pathogens · 2026Article
- The Impact of Mechanical Circulatory Support Devices on White Blood Cell Phenotype and Function.Cardiovascular engineering and technology · 2025Review
- The spatial resolution limit of phagocytosis.Biophysical journal · 2023Article
- Cell-Level Analysis Visualizing Photodynamic Therapy with Porphylipoprotein and Talaporphyrin Sodium.International journal of molecular sciences · 2022Article
- Regulation of Macrophage Foam Cell Formation During Nitrogen Mustard (NM)-Induced Pulmonary Fibrosis by Lung Lipids.Toxicological sciences : an official journal of the Society of Toxicology · 2019Article
- The recycling endosome and bacterial pathogens.Cellular microbiology · 2018Review
- Phagosomal transport depends strongly on phagosome size.Scientific reports · 2017Article
- Isolation of Salmonella typhimurium-containing Phagosomes from Macrophages.Journal of visualized experiments : JoVE · 2017Article
- Persistent bacterial infections and persister cells.Nature reviews. Microbiology · 2017Review
- Macrophages phagocytose nonopsonized silica particles using a unique microtubule-dependent pathway.Molecular biology of the cell · 2015Article
- Phagocytic ability declines with age in adult Drosophila hemocytes.Aging cell · 2014Article
- Structure of the virulence-associated protein VapD from the intracellular pathogen Rhodococcus equi.Acta crystallographica. Section D, Biological crystallography · 2014Article
- From mouth to macrophage: mechanisms of innate immune subversion by Mycobacterium avium subsp. paratuberculosis.Veterinary research · 2014Review
- Production possibility frontiers in phototroph:heterotroph symbioses: trade-offs in allocating fixed carbon pools and the challenges these alternatives present for understanding the acquisition of intracellular habitats.Frontiers in microbiology · 2014Article
- The cellular prion protein negatively regulates phagocytosis and cytokine expression in murine bone marrow-derived macrophages.PloS one · 2014Article
- Plasmin promotes foam cell formation by increasing macrophage catabolism of aggregated low-density lipoprotein.Arteriosclerosis, thrombosis, and vascular biology · 2013Article
- Activation of caspase-1 by the NLRP3 inflammasome regulates the NADPH oxidase NOX2 to control phagosome function.Nature immunology · 2013Article
- Cell biology of infection by Legionella pneumophila.Microbes and infection · 2013Review
- Deciphering the intracellular fate of Propionibacterium acnes in macrophages.BioMed research international · 2013Article
- Role of extracellular nucleotides in the immune response against intracellular bacteria and protozoan parasites.Microbes and infection · 2012Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Cells of the innate immune system ingest and destroy invading microorganisms by initially engulfing them into a specialized vacuole, known as the phagosome. The membrane of the forming phagosome is similar to the plasmalemma and its contents resemble the extracellular milieu. As such, the nascent phagosome is not competent to kill and eliminate the ingested microorganisms. However, shortly after sealing, the phagosome undergoes a series of rapid and extensive changes in its composition, the result of a sophisticated sequence of membrane fusion and fission reactions. Understanding the molecular basis of these events is of particular importance, since they are often the target of disruption by intracellular parasites such as Mycobacterium, Salmonella and Legionella. The objective of this review is to summarize the current knowledge of the molecular mechanisms underlying phagosomal maturation and its subversion by parasitic microorganisms.
Indexed as
Identifiers
12962275What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.