ArticleThe Journal of clinical investigation2003
Dendritic cells and the intestinal bacterial flora: a role for localized mucosal immune responses.
Article in The Journal of clinical investigation, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
28 citing papers in PubMed.
- IFN-γ drives inflammatory bowel disease pathogenesis through VE-cadherin-directed vascular barrier disruption.The Journal of clinical investigation · 2019Trial
- Megasphaera Elesdenii Dysregulates Colon Epithelial Homeostasis, Aggravates Colitis-Associated Tumorigenesis.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- Article
- Dextran Sulphate Sodium Acute Colitis Rat Model: A Suitable Tool for Advancing Our Understanding of Immune and Microbial Mechanisms in the Pathogenesis of Inflammatory Bowel Disease.Veterinary sciences · 2022Article
- The Role of Segmented Filamentous Bacteria in Immune Barrier Maturation of the Small Intestine at Weaning.Frontiers in nutrition · 2021Review
- Angiocrine Regulation of Epithelial Barrier Integrity in Inflammatory Bowel Disease.Frontiers in medicine · 2021Review
- The matter of the reproductive microbiome.Obstetric medicine · 2019Review
- β-Defensins: Farming the Microbiome for Homeostasis and Health.Frontiers in immunology · 2018Review
- Thymic Stromal Lymphopoietin: To Cut a Long Story Short.Cellular and molecular gastroenterology and hepatology · 2017Review
- EpCAM-dependent extracellular vesicles from intestinal epithelial cells maintain intestinal tract immune balance.Nature communications · 2016Article
- Intestinal alkaline phosphatase deficiency leads to lipopolysaccharide desensitization and faster weight gain.Infection and immunity · 2015Article
- Role of secretory IgA in the mucosal sensing of commensal bacteria.Gut microbes · 2014Review
- The intraperitoneal inoculation of Lactobacillus casei in mice induces total protection against Trichinella spiralis infection at low challenge doses.Parasitology research · 2011Article
- Cytokine-induced alterations of α7 nicotinic receptor in colonic CD4 T cells mediate dichotomous response to nicotine in murine models of Th1/Th17- versus Th2-mediated colitis.Journal of immunology (Baltimore, Md. : 1950) · 2011Article
- Innate signaling networks in mucosal IgA class switching.Advances in immunology · 2010Review
- The role of the lactadherin in promoting intestinal DCs development in vivo and vitro.Clinical & developmental immunology · 2010Article
- Probiotics for photoprotection.Dermato-endocrinology · 2009Article
- Exaggerated inflammatory response of primary human myeloid dendritic cells to lipopolysaccharide in patients with inflammatory bowel disease.Clinical and experimental immunology · 2009Article
- Morphology and ontogeny of dendritic cells in rats at different development periods.World journal of gastroenterology · 2009Article
- Rapid dendritic cell mobilization to the large intestinal epithelium is associated with resistance to Trichuris muris infection.Journal of immunology (Baltimore, Md. : 1950) · 2009Article
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Mammals coexist in an overall symbiotic relationship with a complex array of commensal bacterial flora that colonizes the gastrointestinal tract. These intestinal bacteria interface with cells of the mucosal immune system, including DCs. Here we discuss mechanisms of interaction between intestinal bacteria and DCs and the role of localized gastrointestinal immune responses.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.