Evidence map›Paper›PMID 12952909›Full record

ArticleThe Journal of clinical investigation2003

Evidence for a bone-kidney axis regulating phosphate homeostasis.

L Darryl Quarles

Abstract readComment
In one paragraph

Article in The Journal of clinical investigation, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 50 papers.

0numbers the graph read from it
0cells of the map it votes in
50citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

50 citing papers in PubMed.

  1. Effects of hPTH(1-34) infusion on circulating serum phosphate, 1,25-dihydroxyvitamin D, and FGF23 levels in healthy men.Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2009
    Trial
  2. FGF-based drug discovery: advances and challenges.Nature reviews. Drug discovery · 2025
    Review
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Fibroblast growth factor 23 and α-Klotho co-dependent and independent functions.Current opinion in nephrology and hypertension · 2019
    Review
  13. Osteomalacia, renal Fanconi syndrome, and bone tumor.The Journal of international medical research · 2018
    Article
  14. Cardiovascular Effects of Renal Distal Tubule Deletion of the FGF Receptor 1 Gene.Journal of the American Society of Nephrology : JASN · 2018
    Article
  15. Review
  16. Article
  17. Article
  18. Reports of 17 Chinese patients with tumor-induced osteomalacia.Journal of bone and mineral metabolism · 2017
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

1 author.

L Darryl QuarlesDepartment of Medicine, Duke University Medical Center, Durham, North Carolina 27710, USA. quarl001@mc.duke.edu

Funding

Regulation and Function of FGF23R01AR045955 · NIAMS · UNIVERSITY OF TENNESSEE HEALTH SCI CTR · PI QUARLES, L DARRYL · 1999 to 2016
$4.8M
NIAMS NIH HHS R01 AR045955NIAMS NIH HHS R01-AR45955
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Extracellular Matrix ProteinsHomeostasisAnimalsBone and BonesCalcification, PhysiologicFibroblast Growth Factor-23Fibroblast Growth FactorsGlycoproteinsHumansKidneyMicePhosphatesPhosphoproteinsProto-Oncogene ProteinsSecreted Frizzled-Related ProteinsExtracellular Matrix ProteinsFibroblast Growth Factor-23Fibroblast Growth FactorsGlycoproteinsMEPE protein, humanPhosphatesPhosphoproteinsProto-Oncogene ProteinsSecreted Frizzled-Related ProteinsSFRP4 protein, humanSfrp4 protein, mouse

Identifiers

PMID12952909
PMCPMC182218

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.