ArticleProceedings of the National Academy of Sciences of the United States of America2003
Systemins: a functionally defined family of peptide signals that regulate defensive genes in Solanaceae species.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 68 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
68 citing papers in PubMed, 216 citations in OpenAlex.
- The zig-zag model of molecular defense and counterdefense in plant-herbivore interactions.Planta · 2026Review
- Processing and release of endogenous immunogenic peptide signals.The Plant journal : for cell and molecular biology · 2026Review
- Advances of Peptides for Plant Immunity.Plants (Basel, Switzerland) · 2025Review
- Engineering and application of multiepitope recombinant proteins to enhance resistance toFrontiers in plant science · 2025Article
- Pathogen elicitor peptide (pep), systemin, and their receptors in tomato: sequence analysis sheds light on standing disagreements about biotic stress signaling components.BMC plant biology · 2024Article
- Regulation of stomatal development by epidermal, subepidermal and long-distance signals.Plant molecular biology · 2024Review
- Bioassays for Identifying and Characterizing Plant Regulatory Peptides.Biomolecules · 2023Review
- Genomic and metabolic profiling of two tomato contrasting cultivars for tolerance to Tuta absoluta.Planta · 2023Article
- Ecotin: A versatile protease inhibitor of bacteria and eukaryotes.Frontiers in microbiology · 2023Review
- The simultaneous perception of self- and non-self-danger signals potentiates plant innate immunity responses.Planta · 2022Article
- Effector-mediated plant-virus-vector interactions.The Plant cell · 2022Review
- Article
- Not Only Systemin: Prosystemin Harbors Other Active Regions Able to Protect Tomato Plants.Frontiers in plant science · 2022Article
- Stress-induced activation of receptor signaling by protease-mediated cleavage.The Biochemical journal · 2021Article
- Article
- Phytocytokines function as immunological modulators of plant immunity.Stress biology · 2021Review
- Colonization ofJournal of fungi (Basel, Switzerland) · 2020Article
- Breaking Bad News: Dynamic Molecular Mechanisms of Wound Response in Plants.Frontiers in plant science · 2020Review
- Ethnobotany and Antimicrobial Peptides From Plants of the Solanaceae Family: An Update and Future Prospects.Frontiers in pharmacology · 2020Review
- Jasmonic Acid Signaling Pathway in Plants.International journal of molecular sciences · 2019Review
8 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Numerous plant species have been known for decades that respond to herbivore attacks by systemically synthesizing defensive chemicals to protect themselves from predators. The nature of systemic wound signals remained obscure until 1991, when an 18-aa peptide called systemin was isolated from tomato leaves and shown to be a primary signal for systemic defense. More recently, two new hydroxyproline-rich, glycosylated peptide defense signals have been isolated from tobacco leaves, and three from tomato leaves. Because of their origins in plants, small sizes, hydroxyproline contents (tomato systemin is proline-rich), and defense-signaling activities, the new peptides are included in a functionally defined family of signals collectively called systemins. Here, we review structural and biological properties of the systemin family, and discuss their possible roles in systemic wound signaling.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.