Evidence map›Paper›PMID 12948892›Full record

ArticleEnvironmental health perspectives2003

The relationship between air pollution from heavy traffic and allergic sensitization, bronchial hyperresponsiveness, and respiratory symptoms in Dutch schoolchildren.

Nicole A H Janssen, Bert Brunekreef, Patricia van Vliet, Francee Aarts, Kees Meliefste, Hendrik Harssema, Paul Fischer

Registry-linked trialOpen access · diamondAbstract read
In one paragraph

Article in Environmental health perspectives, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01699204 (Effects of Diesel Exhaust on Airways), which is not on this map. Cited by 96 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
96citing papers in PubMed, 3 pooled it
15.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01699204 nacompletednot on this mapstarted 2007, after this paper: background citation

Effects of Diesel Exhaust on Airways

TypeinterventionalSponsorUniversity of British ColumbiaRan2007 to 2011Enrolled26ConditionsAsthmaArmsN-acetylcysteine, Diesel exhaust, Filtered air
3 · Its place in the literature

Who cites it

96 citing papers in PubMed, 3 syntheses or guidelines pooled it, 424 citations in OpenAlex.

  1. Pooled it
  2. [Air pollution and atopic eczema : Systematic review of findings from environmental epidemiological studies].Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete · 2019
    Pooled it
  3. Pooled it
  4. Review
  5. Article
  6. Article
  7. Life Course of Asthma.Advances in experimental medicine and biology · 2023
    Article
  8. Prenatal Exposure toEnvironmental health perspectives · 2023
    Article
  9. Article
  10. Article
  11. Long-Term Exposure to Ambient Fine Particulate Matter (Environmental health perspectives · 2019
    Article
  12. Article
  13. Review
  14. Review
  15. Article
  16. A Comparison of the Health Effects of Ambient Particulate Matter Air Pollution from Five Emission Sources.International journal of environmental research and public health · 2018
    Review
  17. Article
  18. Article
  19. Article
  20. NO to NOAtmospheric environment (Oxford, England : 1994) · 2017
    Article

36 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Nicole A H JanssenDepartment of Environmental Epidemiology, Institute for Risk Assessment Sciences, University of Utrecht, PO Box 80176, 3508 TD Utrecht, The Netherlands.
Bert Brunekreef
Patricia van Vliet
Francee Aarts
Kees Meliefste
Hendrik Harssema
Paul Fischer
Utrecht University · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Studies have suggested that children living close to busy roads may have impaired respiratory health. This study was designed to test the hypothesis that exposure to exhaust from heavy traffic in particular is related to childhood respiratory health. Children attending 24 schools located within 400 m from busy motorways were investigated. The motorways carried between 5,190 and 22,326 trucks per weekday and between 30,399 and 155,656 cars per day. Locations were chosen so that the correlation between truck and car traffic counts was low. Air pollution measurements were performed at the schools for 1 year. Respiratory symptoms were collected by parent-completed questionnaire. Sensitization to common allergens was measured by serum immunoglobulin E and skin prick tests. Bronchial hyperresponsiveness (BHR) was measured with a hypertonic saline challenge. Respiratory symptoms were increased near motorways with high truck but not high car traffic counts. They were also related to air pollutants that increased near motorways with high truck traffic counts. Lung function and BHR were not related to pollution. Sensitization to pollen increased in relation to truck but not car traffic counts. The relation between symptoms and measures of exposure to (truck) traffic-related air pollution were almost entirely restricted to children with BHR and/or sensitization to common allergens, indicating that these are a sensitive subgroup among all children for these effects.

Indexed as

Environmental ExposureGeographic Information SystemsAir PollutantsAllergensBronchial HyperreactivityChildFemaleHumansHypersensitivityImmunoglobulin EMaleMotor VehiclesNetherlandsPollenPrevalenceVehicle EmissionsAir PollutantsAllergensImmunoglobulin EVehicle Emissions

Identifiers

PMID12948892
PMCPMC1241655
OpenAlexW1991432167

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.